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@ARTICLE{Vedelago:169174,
      author       = {J. A. Vedelago$^*$ and F. Mattea and S. Triviño and M. D.
                      M. Montesinos and W. Keil and M. Valente and M. Romero},
      title        = {{S}mart material based on boron crosslinked polymers with
                      potential applications in cancer radiation therapy.},
      journal      = {Scientific reports},
      volume       = {11},
      number       = {1},
      issn         = {2045-2322},
      address      = {[London]},
      publisher    = {Macmillan Publishers Limited, part of Springer Nature},
      reportid     = {DKFZ-2021-01303},
      pages        = {12269},
      year         = {2021},
      note         = {#EA:E040#},
      abstract     = {Organoboron compounds have been playing an increasingly
                      important role in analytical chemistry, material science,
                      health applications, and particularly as functional polymers
                      like boron carriers for cancer therapy. There are two main
                      applications of boron isotopes in radiation cancer therapy,
                      Boron Neutron Capture Therapy and Proton Boron Fusion
                      Therapy. In this study, a novel and original material
                      consisting of a three-dimensional polymer network
                      crosslinked with [Formula: see text]B enriched boric acid
                      molecules is proposed and synthesized. The effects of the
                      exposition to thermal neutrons were studied analyzing
                      changes in the mechanical properties of the proposed
                      material. Dedicated Monte Carlo simulations, based on MCNP
                      and FLUKA main codes, were performed to characterize
                      interactions of the proposed material with neutrons,
                      photons, and charged particles typically present in mixed
                      fields in nuclear reactor irradiations. Experimental results
                      and Monte Carlo simulations were in agreement, thus
                      justifying further studies of this promising material.},
      cin          = {E040},
      ddc          = {600},
      cid          = {I:(DE-He78)E040-20160331},
      pnm          = {315 - Bildgebung und Radioonkologie (POF4-315)},
      pid          = {G:(DE-HGF)POF4-315},
      typ          = {PUB:(DE-HGF)16},
      pubmed       = {pmid:34112821},
      doi          = {10.1038/s41598-021-91413-x},
      url          = {https://inrepo02.dkfz.de/record/169174},
}