TY  - JOUR
AU  - Tönnies, Justus
AU  - Hartmann, Mechthild
AU  - Jäger, Dirk
AU  - Bleyel, Caroline
AU  - Becker, Nikolaus
AU  - Friederich, Hans-Christoph
AU  - Haun, Markus W
TI  - Aggressiveness of Care at the End-of-Life in Cancer Patients and Its Association With Psychosocial Functioning in Bereaved Caregivers.
JO  - Frontiers in oncology
VL  - 11
SN  - 2234-943X
CY  - Lausanne
PB  - Frontiers Media
M1  - DKFZ-2021-01440
SP  - 673147
PY  - 2021
AB  - https://www.drks.de/drks_web/navigate.do?navigationId=trial.HTML</td><td width="150">
AB  - TRIAL_ID=DRKS00022837,DRKS00022837.Intensified oncological treatment for advanced cancer patients at the end-of-life has been specified as aggressiveness of care (AOC) and increased over the past decades. The aims of this study were to 1) determine the frequency of AOC in Central Europe, and 2) investigate differences in mental health outcomes in bereaved caregivers depending on whether the decedent had experienced AOC or not.We conducted a cross-sectional study in a large tertiary comprehensive cancer care center in Germany. Bereaved caregivers provided information about (a) treatment within the last month of life of the deceased cancer patient and (b) their own mental health status, i.e., decision regret, complicated grief, depression, and anxiety. After multiple imputation of missing data, differences in mental health outcomes between AOC-caregivers and non-AOC-caregivers were analyzed in a multivariate analysis of variances.We enrolled 298 bereaved caregivers of deceased cancer patients. AOC occurred in 30.9
KW  - aggressiveness of care (Other)
KW  - cancer (Other)
KW  - caregivers (Other)
KW  - mental health (Other)
KW  - multivariate analysis of variance (Other)
KW  - regret (Other)
LB  - PUB:(DE-HGF)16
C6  - pmid:34150639
C2  - pmc:PMC8212704
DO  - DOI:10.3389/fonc.2021.673147
UR  - https://inrepo02.dkfz.de/record/169360
ER  -