%0 Journal Article
%A Papadimitriou, Nikos
%A Gunter, Marc J
%A Murphy, Neil
%A Gicquiau, Audrey
%A Achaintre, David
%A Brezina, Stefanie
%A Gumpenberger, Tanja
%A Baierl, Andreas
%A Ose, Jennifer
%A Geijsen, Anne Jmr
%A van Roekel, Eline H
%A Gsur, Andrea
%A Gigic, Biljana
%A Habermann, Nina
%A Ulrich, Cornelia M
%A Kampman, Ellen
%A Weijenberg, Matty P
%A Ueland, Per-Magne
%A Kaaks, Rudolf
%A Katzke, Verena
%A Krogh, Vittorio
%A Bueno-de-Mesquita, Bas
%A Ardanaz, Eva
%A Travis, Ruth C
%A Schulze, Matthias B
%A Sánchez, Maria-José
%A Colorado-Yohar, Sandra M
%A Weiderpass, Elisabete
%A Scalbert, Augustin
%A Keski-Rahkonen, Pekka
%T Circulating tryptophan metabolites and risk of colon cancer: results from case-control and prospective cohort studies.
%J International journal of cancer
%V 149
%N 9
%@ 1097-0215
%C Bognor Regis
%I Wiley-Liss
%M DKFZ-2021-01487
%P 1659-1669
%D 2021
%Z 2021 Nov 1;149(9):1659-1669
%X Dysregulation of tryptophan metabolism has been linked to colorectal tumorigenesis, however, epidemiological studies investigating tryptophan metabolites in relation to colorectal cancer risk are limited. We studied associations of plasma tryptophan, serotonin, and kynurenine with colon cancer risk in two studies with cancer patients and controls, and in one prospective cohort: ColoCare Study (110 patients/153 controls), the Colorectal Cancer Study of Austria (CORSA; 46 patients/390 controls), and the European Prospective Investigation into Cancer and Nutrition (EPIC; 456 matched case-control pairs). Logistic regression was used to estimate odds ratios (OR) and 95
%K Tryptophan (Other)
%K colon cancer (Other)
%K kynurenine (Other)
%K plasma (Other)
%K serotonin (Other)
%F PUB:(DE-HGF)16
%9 Journal Article
%$ pmid:34196970
%R 10.1002/ijc.33725
%U https://inrepo02.dkfz.de/record/169665