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| 024 | 7 | _ | |a 10.1002/mp.15096 |2 doi |
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| 024 | 7 | _ | |a 0094-2405 |2 ISSN |
| 024 | 7 | _ | |a 1522-8541 |2 ISSN |
| 024 | 7 | _ | |a 2473-4209 |2 ISSN |
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| 100 | 1 | _ | |a Marot, Mathieu |0 P:(DE-He78)8b9e41d8fdbc77efc053f339f24458f2 |b 0 |e First author |u dkfz |
| 245 | _ | _ | |a Technical Note: On the feasibility of performing dosimetry in target and organ at risk using polymer dosimetry gel and thermoluminescence detectors in an anthropomorphic, deformable and multimodal pelvis phantom. |
| 260 | _ | _ | |a College Park, Md. |c 2021 |b AAPM |
| 336 | 7 | _ | |a article |2 DRIVER |
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| 336 | 7 | _ | |a Journal Article |b journal |m journal |0 PUB:(DE-HGF)16 |s 1642167141_11420 |2 PUB:(DE-HGF) |
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| 336 | 7 | _ | |a Journal Article |0 0 |2 EndNote |
| 500 | _ | _ | |a #EA:E040#LA:E040# / 2021 Sep;48(9):5501-5510 |
| 520 | _ | _ | |a To assess the feasibility of performing dose measurements in the target (prostate) and an adjacent organ at risk (rectum) using polymer dosimetry gel and thermoluminescence detectors (TLDs) in an anthropomorphic, deformable and multimodal pelvis phantom (ADAM PETer).The 3D printed prostate organ surrogate of the ADAM PETer phantom was filled with polymer dosimetry gel. Nine TLD600 (LiF:Mg,Ti) were installed in 3x3 rows on a specifically designed 3D-printed TLD holder. The TLD holder was inserted into the rectum at the level of the prostate and fixed by a partially inflated endorectal balloon. Computed tomography (CT) images were taken and treatment planning was performed. A prescribed dose of 4.5 Gy was delivered to the planning target volume (PTV). The doses measured by the dosimetry gel in the prostate and the TLDs in the rectum ('measured dose') were compared to the doses calculated by the treatment planning system ('planned dose') on a voxel-by-voxel basis.In the prostate organ surrogate, the 3D-γ-index was 97.7% for the 3% dose difference and 3 mm distance to agreement criterium. In the center of the prostate organ surrogate, measured and planned doses showed only minor deviations (<0.1 Gy, corresponding to a percentage error of 2.22%). On the edges of the prostate, slight differences between planned and measured doses were detected with a maximum deviation of 0.24 Gy, corresponding to 5.3% of the prescribed dose. The difference between planned and measured doses in the TLDs was on average 0.08 Gy (range: 0.02-0.21 Gy), corresponding to 1.78% of the prescribed dose (range: 0.44-4.67%).The present study demonstrates the feasibility of using polymer dosimetry gel and TLDs for 3D and 1D dose measurements in the prostate and the rectum organ surrogates in an anthropomorphic, deformable and multimodal phantom. The described methodology might offer new perspectives for end-to-end tests in image-guided adaptive radiotherapy workflows. |
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| 650 | _ | 7 | |a 3D dosimetry |2 Other |
| 650 | _ | 7 | |a TLD |2 Other |
| 650 | _ | 7 | |a anthropomorphic phantom |2 Other |
| 650 | _ | 7 | |a polymer dosimetry gel |2 Other |
| 650 | _ | 7 | |a thermoluminescence dosimetry |2 Other |
| 700 | 1 | _ | |a Elter, Alina |0 P:(DE-He78)d6ff1f04f2e927518e4290cc7dec3133 |b 1 |u dkfz |
| 700 | 1 | _ | |a Mann, Philipp |0 P:(DE-He78)d26409e0d07007daf771142a945102ef |b 2 |u dkfz |
| 700 | 1 | _ | |a Schwahofer, Andrea |0 P:(DE-He78)8918404541688dee7976f7546be900fe |b 3 |u dkfz |
| 700 | 1 | _ | |a Lang, Clemens |0 P:(DE-He78)2c5517db7bc397f9b14ae357a7ce54ff |b 4 |u dkfz |
| 700 | 1 | _ | |a Johnen, Wibke |0 P:(DE-He78)5c55eb63ee2ad2499f7dda0ed08c571b |b 5 |u dkfz |
| 700 | 1 | _ | |a Körber, Stefan A |b 6 |
| 700 | 1 | _ | |a Beuthien-Bauman, Bettina |0 P:(DE-HGF)0 |b 7 |
| 700 | 1 | _ | |a Gillmann, Clarissa |0 P:(DE-He78)a7fec7d808abe2d2579a48df08c0f0ad |b 8 |e Last author |u dkfz |
| 773 | _ | _ | |a 10.1002/mp.15096 |g p. mp.15096 |0 PERI:(DE-600)1466421-5 |n 9 |p 5501-5510 |t Medical physics |v 48 |y 2021 |x 2473-4209 |
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