TY - JOUR AU - Ried-Larsen, Mathias AU - Rasmussen, Martin Gillies AU - Blond, Kim AU - Overvad, Thure F AU - Overvad, Kim AU - Steindorf, Karen AU - Katzke, Verena AU - Andersen, Julie L M AU - Petersen, Kristina E N AU - Aune, Dagfinn AU - Tsilidis, Kostas K AU - Heath, Alicia K AU - Papier, Keren AU - Panico, Salvatore AU - Masala, Giovanna AU - Pala, Valeria AU - Weiderpass, Elisabete AU - Freisling, Heinz AU - Bergmann, Manuela M AU - Verschuren, W M Monique AU - Zamora-Ros, Raul AU - Colorado-Yohar, Sandra M AU - Spijkerman, Annemieke M W AU - Schulze, Matthias B AU - Ardanaz, Eva M A AU - Andersen, Lars Bo AU - Wareham, Nick AU - Brage, Søren AU - Grøntved, Anders TI - Association of Cycling With All-Cause and Cardiovascular Disease Mortality Among Persons With Diabetes: The European Prospective Investigation Into Cancer and Nutrition (EPIC) Study. JO - JAMA internal medicine VL - 181 IS - 9 SN - 2168-6106 CY - Chicago, Ill. PB - American Medical Association M1 - DKFZ-2021-01620 SP - 1196-1205 PY - 2021 N1 - 2021 Sep 1;181(9):1196-1205 AB - Premature death from all causes and cardiovascular disease (CVD) causes is higher among persons with diabetes.To investigate the association between time spent cycling and all-cause and CVD mortality among persons with diabetes, as well as to evaluate the association between change in time spent cycling and risk of all-cause and CVD mortality.This prospective cohort study included 7459 adults with diabetes from the European Prospective Investigation into Cancer and Nutrition study. Questionnaires regarding medical history, sociodemographic, and lifestyle information were administered in 10 Western European countries from 1992 through 2000 (baseline examination) and at a second examination 5 years after baseline. A total of 5423 participants with diabetes completed both examinations. The final updated primary analysis was conducted on November 13, 2020.The primary exposure was self-reported time spent cycling per week at the baseline examination. The secondary exposure was change in cycling status from baseline to the second examination.The primary and secondary outcomes were all-cause and CVD mortality, respectively, adjusted for other physical activity modalities, diabetes duration, and sociodemographic and lifestyle factors.Of the 7459 adults with diabetes included in the analysis, the mean (SD) age was 55.9 (7.7) years, and 3924 (52.6 LB - PUB:(DE-HGF)16 C6 - pmid:34279548 DO - DOI:10.1001/jamainternmed.2021.3836 UR - https://inrepo02.dkfz.de/record/169886 ER -