%0 Journal Article
%A Niedermaier, Tobias
%A Heisser, Thomas
%A Gies, Anton
%A Guo, Feng
%A Amitay, Efrat
%A Hoffmeister, Michael
%A Brenner, Hermann
%T To what extent is male excess risk of advanced colorectal neoplasms explained by known risk factors? Results from a large German screening population.
%J International journal of cancer
%V 149
%N 11
%@ 1097-0215
%C Bognor Regis
%I Wiley-Liss
%M DKFZ-2021-01621
%P 1877-1886
%D 2021
%Z #EA:C070#LA:C070# / 2021 Dec 1;149(11):1877-1886
%X Colorectal cancer (CRC) incidence and prevalence of its precursors are substantially higher among males than among females in most countries but the reasons for the male excess risk are incompletely understood. We aimed to assess to what extent it is explained by known risk factors. Prevalence of advanced neoplasia (AN, i.e. CRC or advanced adenoma) and CRC risk and preventive factors were ascertained among 15,985 participants of screening colonoscopy aged 55-79 years in Germany. Logistic regression was used to calculate odds ratios (ORs) for the association between male sex and AN with and without adjustment for known risk and preventive factors. In age-adjusted comparisons, men had twofold increased risk for AN compared to women (OR=1.98, 95
%K colorectal neoplasia (Other)
%K distal colon (Other)
%K male sex (Other)
%K prevalence (Other)
%K proximal colon (Other)
%F PUB:(DE-HGF)16
%9 Journal Article
%$ pmid:34278571
%R 10.1002/ijc.33742
%U https://inrepo02.dkfz.de/record/169887