TY  - JOUR
AU  - Drake, Virginia
AU  - Bigelow, Elaine
AU  - Fakhry, Carole
AU  - Windon, Melina
AU  - Rooper, Lisa M
AU  - Ha, Patrick
AU  - Miles, Brett
AU  - Gourin, Christine
AU  - Mandal, Rajarsi
AU  - Mydlarz, Wojciech
AU  - London, Nyall
AU  - Vosler, Peter S
AU  - Yavvari, Siddhartha
AU  - Troy, Tanya
AU  - Waterboer, Tim
AU  - Eisele, David W
AU  - D'Souza, Gypsyamber
TI  - Biologic and behavioral associations of estrogen receptor alpha positivity in head and neck squamous cell carcinoma.
JO  - Oral oncology
VL  - 121
SN  - 1368-8375
CY  - Amsterdam [u.a.]
PB  - Elsevier Science
M1  - DKFZ-2021-01685
SP  - 105461
PY  - 2021
N1  - 2021 Oct;121:105461
AB  - Tumor HPV status is an established independent prognostic marker for oropharynx cancer (OPC). Recent studies have reported that tumor estrogen receptor alpha (ERα) positivity is also associated with prognosis independent of HPV. Little is known about the biologic and behavioral predictors of ERα positivity in head and neck squamous cell cancer (HNSCC). We therefore explored this in a multicenter prospective cohort study.Participants with HNSCC completed a survey and provided a blood sample. Tumor samples were tested for ERα using immunohistochemistry. ERα positivity was defined as ≥1
KW  - Estrogen receptor alpha (Other)
KW  - Head and neck neoplasms (Other)
KW  - Oropharyngeal neoplasms (Other)
KW  - Papillomaviridae (Other)
KW  - Tumor biomarkers (Other)
LB  - PUB:(DE-HGF)16
C6  - pmid:34304004
DO  - DOI:10.1016/j.oraloncology.2021.105461
UR  - https://inrepo02.dkfz.de/record/169985
ER  -