TY  - JOUR
AU  - Rühle, Alexander
AU  - Tkotsch, Elisabeth
AU  - Mravlag, Rainer
AU  - Haehl, Erik
AU  - Spohn, Simon K B
AU  - Zamboglou, Constantinos
AU  - Huber, Peter E
AU  - Debus, Jürgen
AU  - Grosu, Anca-Ligia
AU  - Sprave, Tanja
AU  - Nicolay, Nils
TI  - Low-dose radiotherapy for painful osteoarthritis of the elderly: A multicenter analysis of 970 patients with 1185 treated sites.
JO  - Strahlentherapie und Onkologie
VL  - 197
IS  - 10
SN  - 1439-099X
CY  - Heidelberg
PB  - Springer Medizin
M1  - DKFZ-2021-01747
SP  - 895-902
PY  - 2021
N1  - #EA:E055#LA:E055# / 2021 Oct;197(10):895-902
AB  - Painful osteoarthritis is common in elderly patients, and low-dose radiotherapy has been demonstrated to provide effective symptomatic treatment. We examined the analgesic effects of low-dose radiotherapy for osteoarthritis in the elderly aiming to reveal potential differences in the response rates relating to increasing age.A retrospective analysis was performed at two university hospitals including elderly patients (≥ 65 years) undergoing radiotherapy for osteoarthritis between 2008 and 2020. Pain intensity and response were quantified using the numerical rating scale (NRS) and the Pannewitz score. Age groups were defined for young old (65-74 years), older old (75-84 years), and oldest old patients (≥ 85 years).In all, 970 patients with 1185 treated sites and a median age of 76 years were analyzed. Mean NRS was 66 at baseline (t0), 53 after radiotherapy (t1), and 44 at first follow-up (t2) (p < 0.001 for t0-t1, t1-t2, and t0-t2). At t1, 1.5
KW  - Benign diseases (Other)
KW  - Elderly patients (Other)
KW  - Joint disorder (Other)
KW  - Low-dose radiotherapy (Other)
KW  - Osteoarthritis (Other)
LB  - PUB:(DE-HGF)16
C6  - pmid:34342662
DO  - DOI:10.1007/s00066-021-01816-y
UR  - https://inrepo02.dkfz.de/record/170084
ER  -