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000170229 1001_ $$aWeber, Marc-André$$b0
000170229 245__ $$a7 Tesla Chlor (35Cl) und Natrium (23Na) MR-Bildgebung eines Enchondroms.
000170229 260__ $$aStuttgart [u.a.]$$bThieme$$c2021
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000170229 500__ $$a#LA:E020# / 2021 Oct;193(10):1207-1211
000170229 520__ $$aWe demonstrated the feasibility of 7 Tesla sodium (23Na) and chlorine (35Cl) MRI of a solitary enchondroma. For this, we established dedicated sequences on a 7-Tesla whole-body system with the following key parameters for 35Cl MRI: TE/TR = 0.35/60 ms, TRO = 5 ms, α = 90°, Δx3 = (6 mm)3, 3 averages, Tacq = 30 min and for 23Na MRI: TE/TR = 0.4/101 ms, TRO = 10ms; α = 90°; Δx3 = (1.9 mm)3, 3 averages, Tacq = 30 min 18 s. The measured apparent Na+ concentration was 255 mmol/l and was approximately 7-fold higher than the apparent Cl- concentration with about 36 mmol/l. Additionally, repeated proton MRI examinations demonstrated constant but subtle growth (≈ 0.65 ml/year) over 14 years. In conclusion, enchondromas obviously have a high contrast-to-noise ratio when compared with the normal bone marrow in 23Na and 35Cl MRI, which may contribute to detection and differentiation in unclear or subtle cases. KEY POINTS:: · High magnetic field strengths (e. g., 7 Tesla) enable sodium (23Na) and chlorine (35Cl) MRI of solitary cartilage-forming tumors like enchondromas with nominal spatial resolutions of (1.9 mm)3 (23Na MRI) and (6 mm)3 (35Cl MRI).. · Measured median tumoral apparent Na+ and Cl- concentrations were nearly 13 times higher and 3 times higher than in normal muscle tissue, respectively.. · Enchondromas have a high contrast-to-noise-ratio when compared with the normal bone marrow in 23Na and 35Cl MRI, which may contribute to detection and differentiation in unclear or subtle cases.. CITATION FORMAT: · Weber M, Seyler L, Nagel AM. 7 Tesla Chlorine (35Cl) and Sodium (23Na) MR Imaging of an Enchondroma. Fortschr Röntgenstr 2021; DOI: 10.1055/a-1472-6730.
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000170229 7001_ $$aSeyler, Lisa$$b1
000170229 7001_ $$0P:(DE-He78)054fd7a5195b75b11fbdc5c360276011$$aNagel, Armin$$b2$$eLast author$$udkfz
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