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| 001 | 170229 | ||
| 005 | 20240229133709.0 | ||
| 024 | 7 | _ | |a 10.1055/a-1472-6730 |2 doi |
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| 100 | 1 | _ | |a Weber, Marc-André |b 0 |
| 245 | _ | _ | |a 7 Tesla Chlor (35Cl) und Natrium (23Na) MR-Bildgebung eines Enchondroms. |
| 260 | _ | _ | |a Stuttgart [u.a.] |c 2021 |b Thieme |
| 336 | 7 | _ | |a article |2 DRIVER |
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| 500 | _ | _ | |a #LA:E020# / 2021 Oct;193(10):1207-1211 |
| 520 | _ | _ | |a We demonstrated the feasibility of 7 Tesla sodium (23Na) and chlorine (35Cl) MRI of a solitary enchondroma. For this, we established dedicated sequences on a 7-Tesla whole-body system with the following key parameters for 35Cl MRI: TE/TR = 0.35/60 ms, TRO = 5 ms, α = 90°, Δx3 = (6 mm)3, 3 averages, Tacq = 30 min and for 23Na MRI: TE/TR = 0.4/101 ms, TRO = 10ms; α = 90°; Δx3 = (1.9 mm)3, 3 averages, Tacq = 30 min 18 s. The measured apparent Na+ concentration was 255 mmol/l and was approximately 7-fold higher than the apparent Cl- concentration with about 36 mmol/l. Additionally, repeated proton MRI examinations demonstrated constant but subtle growth (≈ 0.65 ml/year) over 14 years. In conclusion, enchondromas obviously have a high contrast-to-noise ratio when compared with the normal bone marrow in 23Na and 35Cl MRI, which may contribute to detection and differentiation in unclear or subtle cases. KEY POINTS:: · High magnetic field strengths (e. g., 7 Tesla) enable sodium (23Na) and chlorine (35Cl) MRI of solitary cartilage-forming tumors like enchondromas with nominal spatial resolutions of (1.9 mm)3 (23Na MRI) and (6 mm)3 (35Cl MRI).. · Measured median tumoral apparent Na+ and Cl- concentrations were nearly 13 times higher and 3 times higher than in normal muscle tissue, respectively.. · Enchondromas have a high contrast-to-noise-ratio when compared with the normal bone marrow in 23Na and 35Cl MRI, which may contribute to detection and differentiation in unclear or subtle cases.. CITATION FORMAT: · Weber M, Seyler L, Nagel AM. 7 Tesla Chlorine (35Cl) and Sodium (23Na) MR Imaging of an Enchondroma. Fortschr Röntgenstr 2021; DOI: 10.1055/a-1472-6730. |
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| 700 | 1 | _ | |a Seyler, Lisa |b 1 |
| 700 | 1 | _ | |a Nagel, Armin |0 P:(DE-He78)054fd7a5195b75b11fbdc5c360276011 |b 2 |e Last author |u dkfz |
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