000170243 001__ 170243
000170243 005__ 20240229133710.0
000170243 0247_ $$2doi$$a10.1002/mrm.28952
000170243 0247_ $$2pmid$$apmid:34399002
000170243 0247_ $$2ISSN$$a0740-3194
000170243 0247_ $$2ISSN$$a1522-2594
000170243 0247_ $$2altmetric$$aaltmetric:111907343
000170243 037__ $$aDKFZ-2021-01851
000170243 041__ $$aEnglish
000170243 082__ $$a610
000170243 1001_ $$00000-0003-3618-9610$$aAigner, Christoph Stefan$$b0
000170243 245__ $$aCalibration-free pTx of the human heart at 7T via 3D universal pulses.
000170243 260__ $$aNew York, NY [u.a.]$$bWiley-Liss$$c2022
000170243 3367_ $$2DRIVER$$aarticle
000170243 3367_ $$2DataCite$$aOutput Types/Journal article
000170243 3367_ $$0PUB:(DE-HGF)16$$2PUB:(DE-HGF)$$aJournal Article$$bjournal$$mjournal$$s1642420118_22337
000170243 3367_ $$2BibTeX$$aARTICLE
000170243 3367_ $$2ORCID$$aJOURNAL_ARTICLE
000170243 3367_ $$00$$2EndNote$$aJournal Article
000170243 500__ $$a#LA:E020# / 2022 Jan;87(1):70-84
000170243 520__ $$aMRI at ultra-high fields in the human body is highly challenging and requires lengthy calibration times to compensate for spatially heterogeneous B 1 + profiles. This study investigates the feasibility of using pre-computed universal pulses for calibration-free homogeneous 3D flip angle distribution in the human heart at 7T.Twenty-two channel-wise 3D B 1 + data sets were acquired under free-breathing in 19 subjects to generate a library for an offline universal pulse (UP) design (group 1: 12 males [M] and 7 females [F], 21-66 years, 19.8-28.3 kg/m2 ). Three of these subjects (2M/1F, 21-33 years, 20.8-23.6 kg/m2 ) were re-scanned on different days. A 4kT-points UP optimized for the 22 channel-wise 3D B 1 + data sets in group 1 (UP22-4kT) is proposed and applied at 7T in 9 new and unseen subjects (group 2: 4M/5F, 25-56 years, 19.5-35.3 kg/m2 ). Multiple tailored and universal static and dynamic parallel-transmit (pTx) pulses were designed and evaluated for different permutations of the B 1 + data sets in group 1 and 2.The proposed UP22-4kT provides low B 1 + variation in all subjects, seen and unseen, without severe signal drops. Experimental data at 7T acquired with UP22-4kT shows comparable image quality as data acquired with tailored-4kT pulses and demonstrates successful calibration-free pTx of the human heart.UP22-4kT allows for calibration-free homogeneous flip angle distributions across the human heart at 7T. Large inter-subject variations because of sex, age, and body mass index are well tolerated. The proposed universal pulse removes the need for lengthy (10-15 min) calibration scans and therefore has the potential to bring body imaging at 7T closer to the clinical application.
000170243 536__ $$0G:(DE-HGF)POF4-315$$a315 - Bildgebung und Radioonkologie (POF4-315)$$cPOF4-315$$fPOF IV$$x0
000170243 588__ $$aDataset connected to CrossRef, PubMed, , Journals: inrepo01.inet.dkfz-heidelberg.de
000170243 650_7 $$2Other$$a7 Tesla
000170243 650_7 $$2Other$$abody MRI
000170243 650_7 $$2Other$$aheart
000170243 650_7 $$2Other$$aparallel transmission
000170243 650_7 $$2Other$$auniversal pulse
000170243 7001_ $$00000-0002-1610-909X$$aDietrich, Sebastian$$b1
000170243 7001_ $$00000-0003-1310-2631$$aSchaeffter, Tobias$$b2
000170243 7001_ $$0P:(DE-He78)19e2d877276b0e5eec11cdfc1789a55e$$aSchmitter, Sebastian$$b3$$eLast author$$udkfz
000170243 773__ $$0PERI:(DE-600)1493786-4$$a10.1002/mrm.28952$$gp. mrm.28952$$n1$$p70-84$$tMagnetic resonance in medicine$$v87$$x1522-2594$$y2022
000170243 909CO $$ooai:inrepo02.dkfz.de:170243$$pVDB
000170243 9101_ $$0I:(DE-588b)2036810-0$$6P:(DE-He78)19e2d877276b0e5eec11cdfc1789a55e$$aDeutsches Krebsforschungszentrum$$b3$$kDKFZ
000170243 9131_ $$0G:(DE-HGF)POF4-315$$1G:(DE-HGF)POF4-310$$2G:(DE-HGF)POF4-300$$3G:(DE-HGF)POF4$$4G:(DE-HGF)POF$$aDE-HGF$$bGesundheit$$lKrebsforschung$$vBildgebung und Radioonkologie$$x0
000170243 9141_ $$y2021
000170243 915__ $$0StatID:(DE-HGF)3001$$2StatID$$aDEAL Wiley$$d2021-01-27$$wger
000170243 915__ $$0StatID:(DE-HGF)0160$$2StatID$$aDBCoverage$$bEssential Science Indicators$$d2021-01-27
000170243 915__ $$0StatID:(DE-HGF)1190$$2StatID$$aDBCoverage$$bBiological Abstracts$$d2021-01-27
000170243 915__ $$0StatID:(DE-HGF)0113$$2StatID$$aWoS$$bScience Citation Index Expanded$$d2021-01-27
000170243 915__ $$0StatID:(DE-HGF)0420$$2StatID$$aNationallizenz$$d2022-11-08$$wger
000170243 915__ $$0StatID:(DE-HGF)0200$$2StatID$$aDBCoverage$$bSCOPUS$$d2022-11-08
000170243 915__ $$0StatID:(DE-HGF)0300$$2StatID$$aDBCoverage$$bMedline$$d2022-11-08
000170243 915__ $$0StatID:(DE-HGF)0199$$2StatID$$aDBCoverage$$bClarivate Analytics Master Journal List$$d2022-11-08
000170243 915__ $$0StatID:(DE-HGF)0150$$2StatID$$aDBCoverage$$bWeb of Science Core Collection$$d2022-11-08
000170243 915__ $$0StatID:(DE-HGF)1050$$2StatID$$aDBCoverage$$bBIOSIS Previews$$d2022-11-08
000170243 915__ $$0StatID:(DE-HGF)1110$$2StatID$$aDBCoverage$$bCurrent Contents - Clinical Medicine$$d2022-11-08
000170243 915__ $$0StatID:(DE-HGF)1030$$2StatID$$aDBCoverage$$bCurrent Contents - Life Sciences$$d2022-11-08
000170243 915__ $$0StatID:(DE-HGF)0100$$2StatID$$aJCR$$bMAGN RESON MED : 2021$$d2022-11-08
000170243 915__ $$0StatID:(DE-HGF)9900$$2StatID$$aIF < 5$$d2022-11-08
000170243 9201_ $$0I:(DE-He78)E020-20160331$$kE020$$lE020 Med. Physik in der Radiologie$$x0
000170243 980__ $$ajournal
000170243 980__ $$aVDB
000170243 980__ $$aI:(DE-He78)E020-20160331
000170243 980__ $$aUNRESTRICTED