%0 Journal Article
%A Schöttker, Ben
%A Gao, Xin
%A Jansen, Eugène Hjm
%A Brenner, Hermann
%T Associations of Human Colorectal Adenoma with Serum Biomarkers of Body Iron Stores, Inflammation and Antioxidant Protein Thiols.
%J Antioxidants
%V 10
%N 8
%@ 2076-3921
%C Basel
%I MDPI
%M DKFZ-2021-01944
%P 1195
%D 2021
%Z #EA:C070#LA:C070#
%X Red and processed meat consumption and obesity are established risk factors for colorectal adenoma (CRA). Adverse changes in biomarkers of body iron stores (total serum iron, ferritin, transferrin and transferrin saturation), inflammation (high-sensitivity C-reactive protein [hs-CRP]) and anti-oxidative capacity (total of thiol groups (-S-H) of proteins [SHP]) might reflect underlying mechanisms that could explain the association of red/processed meat consumption and obesity with CRA. Overall, 100 CRA cases (including 71 advanced cases) and 100 CRA-free controls were frequency-matched on age and sex and were selected from a colonoscopy screening cohort. Odds ratios (OR) and 95
%K C-reactive protein (Other)
%K colorectal adenoma (Other)
%K ferritin (Other)
%K iron (Other)
%K thiols (Other)
%K transferrin saturation (Other)
%F PUB:(DE-HGF)16
%9 Journal Article
%$ pmid:34439443
%2 pmc:PMC8388983
%R 10.3390/antiox10081195
%U https://inrepo02.dkfz.de/record/170451