TY  - JOUR
AU  - Schöttker, Ben
AU  - Gao, Xin
AU  - Jansen, Eugène Hjm
AU  - Brenner, Hermann
TI  - Associations of Human Colorectal Adenoma with Serum Biomarkers of Body Iron Stores, Inflammation and Antioxidant Protein Thiols.
JO  - Antioxidants
VL  - 10
IS  - 8
SN  - 2076-3921
CY  - Basel
PB  - MDPI
M1  - DKFZ-2021-01944
SP  - 1195
PY  - 2021
N1  - #EA:C070#LA:C070#
AB  - Red and processed meat consumption and obesity are established risk factors for colorectal adenoma (CRA). Adverse changes in biomarkers of body iron stores (total serum iron, ferritin, transferrin and transferrin saturation), inflammation (high-sensitivity C-reactive protein [hs-CRP]) and anti-oxidative capacity (total of thiol groups (-S-H) of proteins [SHP]) might reflect underlying mechanisms that could explain the association of red/processed meat consumption and obesity with CRA. Overall, 100 CRA cases (including 71 advanced cases) and 100 CRA-free controls were frequency-matched on age and sex and were selected from a colonoscopy screening cohort. Odds ratios (OR) and 95
KW  - C-reactive protein (Other)
KW  - colorectal adenoma (Other)
KW  - ferritin (Other)
KW  - iron (Other)
KW  - thiols (Other)
KW  - transferrin saturation (Other)
LB  - PUB:(DE-HGF)16
C6  - pmid:34439443
C2  - pmc:PMC8388983
DO  - DOI:10.3390/antiox10081195
UR  - https://inrepo02.dkfz.de/record/170451
ER  -