%0 Journal Article
%A Li, Xinjun
%A Koskinen, Anni I
%A Hemminki, Otto
%A Försti, Asta
%A Sundquist, Jan
%A Sundquist, Kristina
%A Hemminki, Kari
%T Family History of Head and Neck Cancers.
%J Cancers
%V 13
%N 16
%@ 2072-6694
%C Basel
%I MDPI
%M DKFZ-2021-01947
%P 4115
%D 2021
%X Head and neck cancers (HNCs) encompass a heterogeneous group of cancers between the mouth and larynx. Familial clustering in HNCs has been described, but how it influences individual sites and to which extent known risk factors, such as human papilloma virus (HPV) infection, may contribute is not well established.We employed standardized incidence ratios (SIRs) to estimate familial risks for HNC with same (concordant) and different (discordant) cancers among first-degree relatives using data from the Swedish Cancer Registry from 1958 to 2018.Incidence for male and female oropharyngeal cancer increased close to four-fold in the past 39 years. Familial HNC was found in 3.4
%K genetic factors (Other)
%K human papilloma virus (Other)
%K oral cancer (Other)
%K pharyngeal cancer (Other)
%K smoking (Other)
%F PUB:(DE-HGF)16
%9 Journal Article
%$ pmid:34439270
%2 pmc:PMC8392405
%R 10.3390/cancers13164115
%U https://inrepo02.dkfz.de/record/170454