%0 Journal Article
%A Hedström, Anna Karin
%A Huang, Jesse
%A Brenner, Nicole
%A Butt, Julia
%A Kockum, Ingrid
%A Waterboer, Tim
%A Olsson, Tomas
%A Alfredsson, Lars
%T Low sun exposure acts synergistically with high EBNA-1 antibody levels in MS etiology.
%J European journal of neurology
%V 28
%N 12
%@ 1351-5101
%C Oxford [u.a.]
%I Wiley-Blackwell
%M DKFZ-2021-01957
%P 4146-4152
%D 2021
%Z 2021 Dec;28(12):4146-4152
%X Among multiple sclerosis (MS) patients, an association has been observed between low levels of vitamin D and high Epstein-Barr nuclear antigen 1 (EBNA-1) antibody levels. However, whether sun exposure/vitamin D moderates the role of Epstein-Barr virus infection in MS etiology is unclear. We aimed to investigate potential synergistic effects between low sun exposure and elevated EBNA-1 antibody levels regarding MS risk.We used a population-based case-control study involving 2017 incident cases of MS and 2443 matched controls. We used logistic regression models to calculate odds ratios of MS with 95
%F PUB:(DE-HGF)16
%9 Journal Article
%$ pmid:34435414
%R 10.1111/ene.15082
%U https://inrepo02.dkfz.de/record/170464