TY  - JOUR
AU  - Hedström, Anna Karin
AU  - Huang, Jesse
AU  - Brenner, Nicole
AU  - Butt, Julia
AU  - Kockum, Ingrid
AU  - Waterboer, Tim
AU  - Olsson, Tomas
AU  - Alfredsson, Lars
TI  - Low sun exposure acts synergistically with high EBNA-1 antibody levels in MS etiology.
JO  - European journal of neurology
VL  - 28
IS  - 12
SN  - 1351-5101
CY  - Oxford [u.a.]
PB  - Wiley-Blackwell
M1  - DKFZ-2021-01957
SP  - 4146-4152
PY  - 2021
N1  - 2021 Dec;28(12):4146-4152
AB  - Among multiple sclerosis (MS) patients, an association has been observed between low levels of vitamin D and high Epstein-Barr nuclear antigen 1 (EBNA-1) antibody levels. However, whether sun exposure/vitamin D moderates the role of Epstein-Barr virus infection in MS etiology is unclear. We aimed to investigate potential synergistic effects between low sun exposure and elevated EBNA-1 antibody levels regarding MS risk.We used a population-based case-control study involving 2017 incident cases of MS and 2443 matched controls. We used logistic regression models to calculate odds ratios of MS with 95
LB  - PUB:(DE-HGF)16
C6  - pmid:34435414
DO  - DOI:10.1111/ene.15082
UR  - https://inrepo02.dkfz.de/record/170464
ER  -