% IMPORTANT: The following is UTF-8 encoded.  This means that in the presence
% of non-ASCII characters, it will not work with BibTeX 0.99 or older.
% Instead, you should use an up-to-date BibTeX implementation like “bibtex8” or
% “biber”.

@ARTICLE{Jia:170518,
      author       = {F. Jia and S. Littin and P. Amrein and H. Yu and A. W.
                      Magill$^*$ and T. A. Kuder$^*$ and S. Bickelhaupt$^*$ and F.
                      Laun and M. E. Ladd$^*$ and M. Zaitsev},
      title        = {{D}esign of a high-performance non-linear gradient coil for
                      diffusion weighted {MRI} of the breast.},
      journal      = {Journal of magnetic resonance},
      volume       = {331},
      issn         = {1090-7807},
      address      = {Amsterdam [u.a.]},
      publisher    = {Elsevier},
      reportid     = {DKFZ-2021-01977},
      pages        = {107052},
      year         = {2021},
      abstract     = {Diffusion-weighted imaging (DWI) in the female breast is a
                      magnetic resonance imaging (MRI) technique that complements
                      clinical routine protocols, and that might provide an
                      independent diagnostic value for specific clinical tasks in
                      breast imaging. To further improve specificity of DWI in the
                      breast, stronger and faster diffusion weighting is
                      advantageous. Here, a dedicated gradient coil is designed,
                      targeted at diffusion weighting in the female breast, with
                      the peak gradient magnitude exceeding that of the current
                      clinical MR scanners by an order of a magnitude. Design of
                      application-tailored gradient coils in MRI has recently
                      attracted increased attention. With the target application
                      in mind, the gradient coil is designed on an irregularly
                      shaped semi-open current-carrying surface. Due to the coil
                      former closely fitting the non-spherical target region,
                      non-linear encoding fields become particularly advantageous
                      for achieving locally exceptionally high gradient strengths.
                      As breast tissue has a predominantly isotropic cellular
                      microstructure, the direction of the diffusion-weighting
                      gradient may be allowed to vary within the target volume.
                      However, due to the quadratic dependency of the b-factor on
                      the gradient strength, variation of the gradient magnitude
                      should be carefully controlled. To achieve the above design
                      goals the corresponding multi-objective optimization problem
                      is reformulated as a constrained optimization, allowing for
                      flexible and precise control of the coil properties. A novel
                      constraint is proposed, limiting gradient magnitude
                      variation within every slice while allowing for variations
                      in both the direction of the gradient within the slice and
                      the magnitude across the slices. These innovations enable
                      the design of a unilateral coil for diffusion weighting in
                      the female breast with local gradient strengths exceeding 1
                      T/m with highly homogeneous diffusion weighting for imaging
                      in the coronal slice orientation.},
      keywords     = {Diffusion weighted imaging (Other) / Gradient coil design
                      (Other) / Magnetic resonance imaging (Other) / Non-linear
                      spatial encoding magnetic fields (Other)},
      cin          = {E020 / E250},
      ddc          = {530},
      cid          = {I:(DE-He78)E020-20160331 / I:(DE-He78)E250-20160331},
      pnm          = {315 - Bildgebung und Radioonkologie (POF4-315)},
      pid          = {G:(DE-HGF)POF4-315},
      typ          = {PUB:(DE-HGF)16},
      pubmed       = {pmid:34478997},
      doi          = {10.1016/j.jmr.2021.107052},
      url          = {https://inrepo02.dkfz.de/record/170518},
}