TY  - JOUR
AU  - Kirches, Elmar
AU  - Sahm, Felix
AU  - Korshunov, Andrey
AU  - Bluecher, Christina
AU  - Waldt, Natalie
AU  - Kropf, Siegfried
AU  - Schrimpf, Daniel
AU  - Sievers, Philipp
AU  - Stichel, Damian
AU  - Schüller, Ulrich
AU  - Schittenhelm, Jens
AU  - Riemenschneider, Markus J
AU  - Karajannis, Matthias A
AU  - Perry, Arie
AU  - Pietsch, Torsten
AU  - Boekhoff, Svenja
AU  - Capper, David
AU  - Beck, Katja
AU  - Paramasivam, Nagarajan
AU  - Schlesner, Matthias
AU  - Brastianos, Priscilla K
AU  - Müller, Hermann L
AU  - Pfister, Stefan M
AU  - Mawrin, Christian
TI  - Molecular profiling of pediatric meningiomas shows tumor characteristics distinct from adult meningiomas.
JO  - Acta neuropathologica
VL  - 142
IS  - 5
SN  - 1432-0533
CY  - Heidelberg
PB  - Springer
M1  - DKFZ-2021-02001
SP  - 873-886 
PY  - 2021
N1  - 2021 Nov;142(5):873-886 
AB  - In contrast to adults, meningiomas are uncommon tumors in childhood and adolescence. Whether adult and pediatric meningiomas differ on a molecular level is unclear. Here we report detailed genomic analyses of 37 pediatric meningiomas by sequencing and DNA methylation profiling. Histologically, the series was dominated by meningioma subtypes with aggressive behavior, with 70
KW  - Meningioma (Other)
KW  - Methylation profile (Other)
KW  - NF2 (Other)
KW  - Targeted sequencing (Other)
LB  - PUB:(DE-HGF)16
C6  - pmid:34495383
DO  - DOI:10.1007/s00401-021-02351-x
UR  - https://inrepo02.dkfz.de/record/170547
ER  -