%0 Journal Article
%A Katzke, Verena
%A Le Cornet, Charlotte
%A Mahfouz, Rayaan
%A Brauer, Bianca
%A Johnson, Theron Scot
%A Canzian, Federico
%A Rebours, Vinciane
%A Boutron-Ruault, Marie-Christine
%A Severi, Gianluca
%A Schulze, Matthias B
%A Olsen, Anja
%A Tjoenneland, Anne
%A Overvad, Kim
%A Crous-Bou, Marta
%A Molina-Montes, Esther
%A Amiano, Pilar
%A Huerta, José María
%A Ardanaz, Eva
%A Perez-Cornago, Aurora
%A Masala, Giovanna
%A Pala, Valeria
%A Tumino, Rosario
%A Sacerdote, Carlotta
%A Panico, Salvatore
%A Bueno-de-Mesquita, Bas
%A Vermeulen, Roel
%A Sund, Malin
%A Franklin, Oskar
%A Christakoudi, Sofia
%A Dossus, Laure
%A Weiderpass, Elisabete
%A Olek, Sven
%A Kaaks, Rudolf
%T Are circulating immune cells a determinant of pancreatic cancer risk? A prospective study using epigenetic cell count measures.
%J Cancer epidemiology, biomarkers & prevention
%V 30
%N 12
%@ 1538-7755
%C Philadelphia, Pa.
%I AACR
%M DKFZ-2021-02133
%P 2179-2187
%D 2021
%Z #EA:C020#LA:C020# / 2021 Dec;30(12):2179-2187
%X Evidence is accumulating that immune cells play a prominent role in pancreatic cancer aetiology but prospective investigations are missing.We conducted a nested case-control study within the European Prospective Investigation into Cancer and Nutrition (EPIC) study with 502 pairs of incident pancreatic cancer cases and matched controls. Relative counts of circulating immune cells (neutrophils and lymphocyte sub-lineages: total CD3+, CD8+, CD4+, and FOXP3+ regulatory T cells (Tregs) relative to nucleated cells, (white blood cells) were measured by qRT-PCR. Odds ratios with 95
%F PUB:(DE-HGF)16
%9 Journal Article
%$ pmid:34548327
%R 10.1158/1055-9965.EPI-21-0169
%U https://inrepo02.dkfz.de/record/176891