TY  - JOUR
AU  - Katzke, Verena
AU  - Le Cornet, Charlotte
AU  - Mahfouz, Rayaan
AU  - Brauer, Bianca
AU  - Johnson, Theron Scot
AU  - Canzian, Federico
AU  - Rebours, Vinciane
AU  - Boutron-Ruault, Marie-Christine
AU  - Severi, Gianluca
AU  - Schulze, Matthias B
AU  - Olsen, Anja
AU  - Tjoenneland, Anne
AU  - Overvad, Kim
AU  - Crous-Bou, Marta
AU  - Molina-Montes, Esther
AU  - Amiano, Pilar
AU  - Huerta, José María
AU  - Ardanaz, Eva
AU  - Perez-Cornago, Aurora
AU  - Masala, Giovanna
AU  - Pala, Valeria
AU  - Tumino, Rosario
AU  - Sacerdote, Carlotta
AU  - Panico, Salvatore
AU  - Bueno-de-Mesquita, Bas
AU  - Vermeulen, Roel
AU  - Sund, Malin
AU  - Franklin, Oskar
AU  - Christakoudi, Sofia
AU  - Dossus, Laure
AU  - Weiderpass, Elisabete
AU  - Olek, Sven
AU  - Kaaks, Rudolf
TI  - Are circulating immune cells a determinant of pancreatic cancer risk? A prospective study using epigenetic cell count measures.
JO  - Cancer epidemiology, biomarkers & prevention
VL  - 30
IS  - 12
SN  - 1538-7755
CY  - Philadelphia, Pa.
PB  - AACR
M1  - DKFZ-2021-02133
SP  - 2179-2187
PY  - 2021
N1  - #EA:C020#LA:C020# / 2021 Dec;30(12):2179-2187
AB  - Evidence is accumulating that immune cells play a prominent role in pancreatic cancer aetiology but prospective investigations are missing.We conducted a nested case-control study within the European Prospective Investigation into Cancer and Nutrition (EPIC) study with 502 pairs of incident pancreatic cancer cases and matched controls. Relative counts of circulating immune cells (neutrophils and lymphocyte sub-lineages: total CD3+, CD8+, CD4+, and FOXP3+ regulatory T cells (Tregs) relative to nucleated cells, (white blood cells) were measured by qRT-PCR. Odds ratios with 95
LB  - PUB:(DE-HGF)16
C6  - pmid:34548327
DO  - DOI:10.1158/1055-9965.EPI-21-0169
UR  - https://inrepo02.dkfz.de/record/176891
ER  -