%0 Journal Article %A Baertsch, Marc-Andrea %A Fougereau, Mathilde %A Hielscher, Thomas %A Sauer, Sandra %A Breitkreutz, Iris %A Jordan, Karin %A Müller-Tidow, Carsten %A Goldschmidt, Hartmut %A Raab, Marc-Steffen %A Hillengass, Jens %A Giesen, Nicola %T Carfilzomib, Lenalidomide, and Dexamethasone Followed by Salvage Autologous Stem Cell Transplant with or without Maintenance for Relapsed or Refractory Multiple Myeloma. %J Cancers %V 13 %N 18 %@ 2072-6694 %C Basel %I MDPI %M DKFZ-2021-02189 %P 4706 %D 2021 %Z #LA:A360# %X Salvage high-dose chemotherapy and autologous stem cell transplantation (HDCT/ASCT) is a treatment option for relapsed and/or refractory multiple myeloma (RRMM). No data are available on salvage HDCT/ASCT following re-induction treatment with state-of-the-art triplet regimens. We retrospectively report on 44 patients receiving salvage HDCT/ASCT following re-induction with carfilzomib/lenalidomide/dexamethasone (KRd). All patients received frontline HDCT/ASCT with median time to progression (TTP1) of 2.9 (1.2-13.5) years, enabling paired comparison of frontline and salvage HDCT/ASCT. After re-induction and before salvage transplant, 25/44 patients (57 %K lenalidomide maintenance (Other) %K multiple myeloma (Other) %K salvage autologous stem cell transplantation (Other) %K salvage high-dose chemotherapy (Other) %F PUB:(DE-HGF)16 %9 Journal Article %$ pmid:34572934 %2 pmc:PMC8472377 %R 10.3390/cancers13184706 %U https://inrepo02.dkfz.de/record/176949