TY  - JOUR
AU  - Klimek, Matthias
AU  - Büchele, Gisela
AU  - Rehm, Martin
AU  - Beyersmann, Jan
AU  - Günther, Klaus-Peter
AU  - Brenner, Hermann
AU  - Stürmer, Til
AU  - Brenner, Rolf E
AU  - Rothenbacher, Dietrich
TI  - Long-term mortality of patients with osteoarthritis after joint replacement: Prognostic value of pre- and postoperative pain and function.
JO  - Arthritis care & research
VL  - 75
IS  - 4
SN  - 0893-7524
CY  - New York, NY [u.a.]
PB  - Wiley
M1  - DKFZ-2021-02435
SP  - 869-875
PY  - 2023
N1  - 2023 Apr;75(4):869-875
AB  - To investigate whether osteoarthritis (OA)-specific assessment values (i.e. Western Ontario and McMaster University Osteoarthritis Index [WOMAC]) and generic pain and function (visual analog scale [VAS], Hanover Functionality Status Questionnaire [FFbH]) measured before and 12 months after arthroplasty are associated with the risk of long-term mortality in a cohort of patients with advanced OA of the hip or knee.The Ulm Osteoarthritis Study was a prospective cohort study of OA patients with unilateral total hip or knee replacement between January 1995 and December 1996. Correlation coefficients were calculated to describe the agreement between the different assessments. Mortality was assessed during the follow-up period (last update: July 2019). Cox proportional regression models were used to estimate hazard ratios (HRs) for mortality after adjusting for covariates.Arthroplasty was accompanied by a clear reduction in pain and improved function throughout all assessments in the 706 included patients. The results of the adjusted Cox models showed no relationship between baseline and follow-up joint-specific WOMAC assessments and long-term mortality. However, an independent increased risk of mortality was found with generic function assessments. In the final adjusted model, the HR for the 12-month follow-up value was 1.79 (95
LB  - PUB:(DE-HGF)16
C6  - pmid:34738320
DO  - DOI:10.1002/acr.24808
UR  - https://inrepo02.dkfz.de/record/177323
ER  -