000177491 001__ 177491 000177491 005__ 20240229133741.0 000177491 0247_ $$2doi$$a10.3389/fimmu.2021.724914 000177491 0247_ $$2pmid$$apmid:34745097 000177491 0247_ $$2pmc$$apmc:PMC8564481 000177491 0247_ $$2altmetric$$aaltmetric:115474883 000177491 037__ $$aDKFZ-2021-02578 000177491 041__ $$aEnglish 000177491 082__ $$a610 000177491 1001_ $$aKaur, Arvinpreet$$b0 000177491 245__ $$aThe Omic Insights on Unfolding Saga of COVID-19. 000177491 260__ $$aLausanne$$bFrontiers Media$$c2021 000177491 3367_ $$2DRIVER$$aarticle 000177491 3367_ $$2DataCite$$aOutput Types/Journal article 000177491 3367_ $$0PUB:(DE-HGF)16$$2PUB:(DE-HGF)$$aJournal Article$$bjournal$$mjournal$$s1637243709_30274$$xReview Article 000177491 3367_ $$2BibTeX$$aARTICLE 000177491 3367_ $$2ORCID$$aJOURNAL_ARTICLE 000177491 3367_ $$00$$2EndNote$$aJournal Article 000177491 520__ $$aThe year 2019 has seen an emergence of the novel coronavirus named severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causing coronavirus disease of 2019 (COVID-19). Since the onset of the pandemic, biological and interdisciplinary research is being carried out across the world at a rapid pace to beat the pandemic. There is an increased need to comprehensively understand various aspects of the virus from detection to treatment options including drugs and vaccines for effective global management of the disease. In this review, we summarize the salient findings pertaining to SARS-CoV-2 biology, including symptoms, hosts, epidemiology, SARS-CoV-2 genome, and its emerging variants, viral diagnostics, host-pathogen interactions, alternative antiviral strategies and application of machine learning heuristics and artificial intelligence for effective management of COVID-19 and future pandemics. 000177491 536__ $$0G:(DE-HGF)POF4-312$$a312 - Funktionelle und strukturelle Genomforschung (POF4-312)$$cPOF4-312$$fPOF IV$$x0 000177491 588__ $$aDataset connected to CrossRef, PubMed, , Journals: inrepo01.inet.dkfz-heidelberg.de 000177491 650_7 $$2Other$$aCOVID-19 000177491 650_7 $$2Other$$aORFs 000177491 650_7 $$2Other$$aSARS-CoV-2 000177491 650_7 $$2Other$$aco-morbidities 000177491 650_7 $$2Other$$amachine learning 000177491 7001_ $$aChopra, Mehak$$b1 000177491 7001_ $$aBhushan, Mahak$$b2 000177491 7001_ $$aGupta, Sonal$$b3 000177491 7001_ $$aKumari P, Hima$$b4 000177491 7001_ $$aSivagurunathan, Narmadhaa$$b5 000177491 7001_ $$aShukla, Nidhi$$b6 000177491 7001_ $$aRajagopal, Shalini$$b7 000177491 7001_ $$aBhalothia, Purva$$b8 000177491 7001_ $$aSharma, Purnima$$b9 000177491 7001_ $$aNaravula, Jalaja$$b10 000177491 7001_ $$aSuravajhala, Renuka$$b11 000177491 7001_ $$aGupta, Ayam$$b12 000177491 7001_ $$aAbbasi, Bilal Ahmed$$b13 000177491 7001_ $$aGoswami, Prittam$$b14 000177491 7001_ $$aSingh, Harpreet$$b15 000177491 7001_ $$aNarang, Rahul$$b16 000177491 7001_ $$aPolavarapu, Rathnagiri$$b17 000177491 7001_ $$aMedicherla, Krishna Mohan$$b18 000177491 7001_ $$aValadi, Jayaraman$$b19 000177491 7001_ $$aKumar S, Anil$$b20 000177491 7001_ $$aChaubey, Gyaneshwer$$b21 000177491 7001_ $$aSingh, Keshav K$$b22 000177491 7001_ $$0P:(DE-He78)b11ccde1801d45d32a6a60f7b396d7dc$$aBandapalli, Obul Reddy$$b23 000177491 7001_ $$aKavi Kishor, Polavarapu Bilhan$$b24 000177491 7001_ $$aSuravajhala, Prashanth$$b25 000177491 773__ $$0PERI:(DE-600)2606827-8$$a10.3389/fimmu.2021.724914$$gVol. 12, p. 724914$$p724914$$tFrontiers in immunology$$v12$$x1664-3224$$y2021 000177491 909CO $$ooai:inrepo02.dkfz.de:177491$$pVDB 000177491 9101_ $$0I:(DE-588b)2036810-0$$6P:(DE-He78)b11ccde1801d45d32a6a60f7b396d7dc$$aDeutsches Krebsforschungszentrum$$b23$$kDKFZ 000177491 9131_ $$0G:(DE-HGF)POF4-312$$1G:(DE-HGF)POF4-310$$2G:(DE-HGF)POF4-300$$3G:(DE-HGF)POF4$$4G:(DE-HGF)POF$$aDE-HGF$$bGesundheit$$lKrebsforschung$$vFunktionelle und strukturelle Genomforschung$$x0 000177491 9141_ $$y2021 000177491 915__ $$0StatID:(DE-HGF)0100$$2StatID$$aJCR$$bFRONT IMMUNOL : 2019$$d2021-01-29 000177491 915__ $$0StatID:(DE-HGF)0200$$2StatID$$aDBCoverage$$bSCOPUS$$d2021-01-29 000177491 915__ $$0StatID:(DE-HGF)0300$$2StatID$$aDBCoverage$$bMedline$$d2021-01-29 000177491 915__ $$0StatID:(DE-HGF)0320$$2StatID$$aDBCoverage$$bPubMed Central$$d2021-01-29 000177491 915__ $$0StatID:(DE-HGF)0501$$2StatID$$aDBCoverage$$bDOAJ Seal$$d2021-01-29 000177491 915__ $$0StatID:(DE-HGF)0500$$2StatID$$aDBCoverage$$bDOAJ$$d2021-01-29 000177491 915__ $$0StatID:(DE-HGF)0030$$2StatID$$aPeer Review$$bDOAJ : Blind peer review$$d2021-01-29 000177491 915__ $$0LIC:(DE-HGF)CCBYNV$$2V:(DE-HGF)$$aCreative Commons Attribution CC BY (No Version)$$bDOAJ$$d2021-01-29 000177491 915__ $$0StatID:(DE-HGF)0199$$2StatID$$aDBCoverage$$bClarivate Analytics Master Journal List$$d2021-01-29 000177491 915__ $$0StatID:(DE-HGF)0160$$2StatID$$aDBCoverage$$bEssential Science Indicators$$d2021-01-29 000177491 915__ $$0StatID:(DE-HGF)0113$$2StatID$$aWoS$$bScience Citation Index Expanded$$d2021-01-29 000177491 915__ $$0StatID:(DE-HGF)0150$$2StatID$$aDBCoverage$$bWeb of Science Core Collection$$d2021-01-29 000177491 915__ $$0StatID:(DE-HGF)9905$$2StatID$$aIF >= 5$$bFRONT IMMUNOL : 2019$$d2021-01-29 000177491 915__ $$0StatID:(DE-HGF)0561$$2StatID$$aArticle Processing Charges$$d2021-01-29 000177491 915__ $$0StatID:(DE-HGF)0700$$2StatID$$aFees$$d2021-01-29 000177491 9201_ $$0I:(DE-He78)B062-20160331$$kB062$$lB062 Pädiatrische Neuroonkologie$$x0 000177491 980__ $$ajournal 000177491 980__ $$aVDB 000177491 980__ $$aI:(DE-He78)B062-20160331 000177491 980__ $$aUNRESTRICTED