% IMPORTANT: The following is UTF-8 encoded. This means that in the presence % of non-ASCII characters, it will not work with BibTeX 0.99 or older. % Instead, you should use an up-to-date BibTeX implementation like “bibtex8” or % “biber”. @ARTICLE{Kaur:177491, author = {A. Kaur and M. Chopra and M. Bhushan and S. Gupta and H. Kumari P and N. Sivagurunathan and N. Shukla and S. Rajagopal and P. Bhalothia and P. Sharma and J. Naravula and R. Suravajhala and A. Gupta and B. A. Abbasi and P. Goswami and H. Singh and R. Narang and R. Polavarapu and K. M. Medicherla and J. Valadi and A. Kumar S and G. Chaubey and K. K. Singh and O. R. Bandapalli$^*$ and P. B. Kavi Kishor and P. Suravajhala}, title = {{T}he {O}mic {I}nsights on {U}nfolding {S}aga of {COVID}-19.}, journal = {Frontiers in immunology}, volume = {12}, issn = {1664-3224}, address = {Lausanne}, publisher = {Frontiers Media}, reportid = {DKFZ-2021-02578}, pages = {724914}, year = {2021}, abstract = {The year 2019 has seen an emergence of the novel coronavirus named severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causing coronavirus disease of 2019 (COVID-19). Since the onset of the pandemic, biological and interdisciplinary research is being carried out across the world at a rapid pace to beat the pandemic. There is an increased need to comprehensively understand various aspects of the virus from detection to treatment options including drugs and vaccines for effective global management of the disease. In this review, we summarize the salient findings pertaining to SARS-CoV-2 biology, including symptoms, hosts, epidemiology, SARS-CoV-2 genome, and its emerging variants, viral diagnostics, host-pathogen interactions, alternative antiviral strategies and application of machine learning heuristics and artificial intelligence for effective management of COVID-19 and future pandemics.}, subtyp = {Review Article}, keywords = {COVID-19 (Other) / ORFs (Other) / SARS-CoV-2 (Other) / co-morbidities (Other) / machine learning (Other)}, cin = {B062}, ddc = {610}, cid = {I:(DE-He78)B062-20160331}, pnm = {312 - Funktionelle und strukturelle Genomforschung (POF4-312)}, pid = {G:(DE-HGF)POF4-312}, typ = {PUB:(DE-HGF)16}, pubmed = {pmid:34745097}, pmc = {pmc:PMC8564481}, doi = {10.3389/fimmu.2021.724914}, url = {https://inrepo02.dkfz.de/record/177491}, }