TY - JOUR AU - Steur, Marinka AU - Johnson, Laura AU - Sharp, Stephen J AU - Imamura, Fumiaki AU - Sluijs, Ivonne AU - Key, Timothy J AU - Wood, Angela AU - Chowdhury, Rajiv AU - Guevara, Marcela AU - Jakobsen, Marianne U AU - Johansson, Ingegerd AU - Koulman, Albert AU - Overvad, Kim AU - Sánchez, Maria-José AU - van der Schouw, Yvonne T AU - Trichopoulou, Antonia AU - Weiderpass, Elisabete AU - Wennberg, Maria AU - Zheng, Ju-Sheng AU - Boeing, Heiner AU - Boer, Jolanda M A AU - Boutron-Ruault, Marie-Christine AU - Ericson, Ulrika AU - Heath, Alicia K AU - Huybrechts, Inge AU - Imaz, Liher AU - Kaaks, Rudolf AU - Krogh, Vittorio AU - Kühn, Tilman AU - Kyrø, Cecilie AU - Masala, Giovanna AU - Melander, Olle AU - Moreno-Iribas, Conchi AU - Panico, Salvatore AU - Quirós, José R AU - Rodríguez-Barranco, Miguel AU - Sacerdote, Carlotta AU - Santiuste, Carmen AU - Skeie, Guri AU - Tjønneland, Anne AU - Tumino, Rosario AU - Verschuren, W M Monique AU - Zamora-Ros, Raul AU - Dahm, Christina C AU - Perez-Cornago, Aurora AU - Schulze, Matthias B AU - Tong, Tammy Y N AU - Riboli, Elio AU - Wareham, Nicholas J AU - Danesh, John AU - Butterworth, Adam S AU - Forouhi, Nita G TI - Dietary Fatty Acids, Macronutrient Substitutions, Food Sources and Incidence of Coronary Heart Disease: Findings From the EPIC-CVD Case-Cohort Study Across Nine European Countries. JO - Journal of the American Heart Association VL - 10 IS - 23 SN - 2047-9980 CY - New York, NY PB - Association M1 - DKFZ-2021-02606 SP - e019814 PY - 2021 N1 - 2021 Dec 7;10(23):e019814 AB - Background There is controversy about associations between total dietary fatty acids, their classes (saturated fatty acids [SFAs], monounsaturated fatty acids, and polyunsaturated fatty acids), and risk of coronary heart disease (CHD). Specifically, the relevance of food sources of SFAs to CHD associations is uncertain. Methods and Results We conducted a case-cohort study involving 10 529 incident CHD cases and a random subcohort of 16 730 adults selected from a cohort of 385 747 participants in 9 countries of the EPIC (European Prospective Investigation into Cancer and Nutrition) study. We estimated multivariable adjusted country-specific hazard ratios (HRs) and 95 KW - coronary heart disease (Other) KW - dietary guidelines (Other) KW - nutritional epidemiology (Other) KW - primary prevention (Other) KW - saturated fat (Other) LB - PUB:(DE-HGF)16 C6 - pmid:34796724 DO - DOI:10.1161/JAHA.120.019814 UR - https://inrepo02.dkfz.de/record/177539 ER -