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@ARTICLE{Boehlen:177750,
      author       = {F. H. Boehlen and I. Maatouk and H.-C. Friederich and B.
                      Schoettker$^*$ and H. Brenner$^*$ and B. Wild},
      title        = {{L}oneliness as a gender-specific predictor of physical and
                      mental health-related quality of life in older adults.},
      journal      = {Quality of life research},
      volume       = {31},
      number       = {7},
      issn         = {0962-9343},
      address      = {Dordrecht [u.a.]},
      publisher    = {Springer Science + Business Media B.V},
      reportid     = {DKFZ-2021-02791},
      pages        = {2023-2033},
      year         = {2022},
      note         = {2022 Jul;31(7):2023-2033},
      abstract     = {Health-related quality of life (HRQOL) in older persons is
                      influenced by physical and mental health, as well as by
                      their social contacts and social support. Older women and
                      men have disparate types of social networks; they each value
                      social ties differently and experience loneliness in unique
                      and personal ways. The aim of this study is, therefore, to
                      determine the longitudinal association between loneliness
                      and social isolation with HRQOL in older people-separated by
                      gender.Data stem from the third and fourth follow-up of the
                      ESTHER study-a population-based cohort study of the older
                      population in Germany. A sample of 2171 older women and men
                      (mean age: 69.3 years, range 57-84 years) were included in
                      this study; HRQOL was assessed by using the Short Form-12
                      questionnaire (SF-12). Data on physical and mental health,
                      loneliness, and social networks were examined in the course
                      of comprehensive home visits by trained study doctors.
                      Gender-specific linear regression analyses were performed to
                      predict physical quality of life (measured by the PCS,
                      physical component score of the SF-12) and mental quality of
                      life (measured by the MCS, mental component score) after
                      three years, adjusted by socioeconomic variables as well as
                      physical, mental, and social well-being.At baseline, PCS was
                      41.3 (SD: 10.0) in women and 42.2 (SD: 9.6) in men (p =
                      .04). MCS was 47.0 (SD: 10.2) in women and 49.6 (SD: 8.6) in
                      men (p < .001). In both genders, PCS and MCS were lower
                      three years later. Loneliness at t0 was negatively
                      associated with both PCS and MCS after three years (t1)
                      among women, and with MCS but not PCS after three years
                      among men. In both genders, the strongest predictor of PCS
                      after three years was PCS at t0 (p < .001), while the
                      strongest predictors of MCS after three years were MCS and
                      PCS at t0.HRQOL in elderly women and men is predicted by
                      different biopsychosocial factors. Loneliness predicts
                      decreased MCS after three years in both genders, but
                      decreased PCS after three years only in women. Thus, a
                      greater impact of loneliness on the health of older women
                      can be surmised and should therefore be considered in the
                      context of their medical care.},
      keywords     = {Gender (Other) / HRQOL (Other) / Loneliness (Other) / Older
                      adults (Other)},
      cin          = {C070},
      ddc          = {100},
      cid          = {I:(DE-He78)C070-20160331},
      pnm          = {313 - Krebsrisikofaktoren und Prävention (POF4-313)},
      pid          = {G:(DE-HGF)POF4-313},
      typ          = {PUB:(DE-HGF)16},
      pubmed       = {pmid:34859354},
      doi          = {10.1007/s11136-021-03055-1},
      url          = {https://inrepo02.dkfz.de/record/177750},
}