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000178310 0247_ $$2doi$$a10.1016/j.clinimag.2021.11.033
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000178310 1001_ $$0P:(DE-He78)c6d2d9aa8c2d4ecd0dd6f96d2f40b7c3$$aTavakoli, Anoshirwan Andrej$$b0$$eFirst author$$udkfz
000178310 245__ $$aPancreatic imaging using diffusivity mapping - Influence of sequence technique on qualitative and quantitative analysis.
000178310 260__ $$aAmsterdam [u.a.]$$bElsevier Science$$c2021
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000178310 520__ $$aTo compare image quality of an optimized diffusion weighted imaging (DWI) sequence with advanced post-processing and motion correction (advanced-EPI) to a standard DWI protocol (standard-EPI) in pancreatic imaging.62 consecutive patients underwent abdominal MRI at 1.5 T were included in this retrospective analysis of data collected as part of an IRB approved study. All patients received a standard-EPI and an advanced-EPI DWI with advanced post-processing and motion correction. Two blinded radiologists evaluated the parameters image quality, detail of parenchyma, sharpness of boundaries and discernibility from adjacent structures on b = 900 s/mm2 images using a Likert-like scale. Segmentation of pancreatic head, body and tail were obtained and apparent diffusion coefficient (ADC) was calculated separately for each region. Apparent tissue-to-background ratio (TBR) was calculated at b = 50 s/mm2 and at b = 900 s/mm2.The advanced-EPI yielded significantly higher scores for pancreatic parameters of image quality, detail level of parenchyma, sharpness of boundaries and discernibility from adjacent structures in comparison to standard-EPI (p < 0.001 for all, kappa = [0.46,0.71]) and was preferred in 96% of the cases when directly compared. ADC of the pancreas was 7% lower in advanced-EPI (1.236 ± 0.152 vs. 1.146 ± 0.126 μm2/ms, p < 0.001). ADC in the pancreatic tail was significantly lower for both sequences compared to head and body (all p < 0.001). There was comparable TBR for both sequences at b = 50 s/mm2 (standard-EPI: 19.0 ± 5.9 vs. advanced-EPI: 19.0 ± 6.4, p = 0.96), whereas at b = 900 s/mm2, TBR was 51% higher for advanced-EPI (standard-EPI: 7.1 ± 2.5 vs. advanced-EPI: 10.8 ± 5.1, p < 0.001).An advanced DWI sequence might increase image quality for focused imaging of the pancreas and providing improved parenchymal detail levels compared to a standard DWI.
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000178310 650_7 $$2Other$$aArtifacts
000178310 650_7 $$2Other$$aDiffusion magnetic resonance imaging
000178310 650_7 $$2Other$$aEcho-planar imaging
000178310 650_7 $$2Other$$aMagnetic resonance imaging
000178310 650_7 $$2Other$$aPancreas
000178310 7001_ $$0P:(DE-He78)b9af25eb669871c3bd619dff8c5c34c0$$aDreher, Constantin$$b1$$udkfz
000178310 7001_ $$0P:(DE-He78)f2017cf9c3356b8a6babaa5943f1e99e$$aMlynarska-Bujny, Anna$$b2
000178310 7001_ $$0P:(DE-He78)59dfdd0ee0a7f0db81535f0781a3a6d6$$aKuder, Tristan Anselm$$b3$$udkfz
000178310 7001_ $$0P:(DE-He78)77bc493068847c689d894d2eda891c0c$$aGnirs, Regula$$b4$$udkfz
000178310 7001_ $$0P:(DE-He78)3d04c8fee58c9ab71f62ff80d06b6fec$$aSchlemmer, Heinz-Peter$$b5$$udkfz
000178310 7001_ $$0P:(DE-He78)d2d971750bce6217eb90fff9b01e61f9$$aBickelhaupt, Sebastian$$b6$$eLast author$$udkfz
000178310 773__ $$0PERI:(DE-600)2004578-5$$a10.1016/j.clinimag.2021.11.033$$gVol. 83, p. 33 - 40$$p33 - 40$$tClinical imaging$$v83$$x0899-7071$$y2021
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