guest ::
| Home > Publications database > Association of circulating leptin, adiponectin, and resistin concentrations with long-term breast cancer prognosis in a German patient cohort. > print |
| Home > Publications database > Association of circulating leptin, adiponectin, and resistin concentrations with long-term breast cancer prognosis in a German patient cohort. > print |
| 001 | 178415 | ||
| 005 | 20240229133806.0 | ||
| 024 | 7 | _ | |2 doi |a 10.1038/s41598-021-02958-w |
| 024 | 7 | _ | |2 pmid |a pmid:34876619 |
| 024 | 7 | _ | |2 pmc |a pmc:PMC8651788 |
| 024 | 7 | _ | |a altmetric:118436933 |2 altmetric |
| 037 | _ | _ | |a DKFZ-2022-00042 |
| 041 | _ | _ | |a English |
| 082 | _ | _ | |a 600 |
| 100 | 1 | _ | |a Obi, Nadia |b 0 |
| 245 | _ | _ | |a Association of circulating leptin, adiponectin, and resistin concentrations with long-term breast cancer prognosis in a German patient cohort. |
| 260 | _ | _ | |a [London] |b Macmillan Publishers Limited, part of Springer Nature |c 2021 |
| 336 | 7 | _ | |2 DRIVER |a article |
| 336 | 7 | _ | |2 DataCite |a Output Types/Journal article |
| 336 | 7 | _ | |0 PUB:(DE-HGF)16 |2 PUB:(DE-HGF) |a Journal Article |b journal |m journal |s 1641821277_5388 |
| 336 | 7 | _ | |2 BibTeX |a ARTICLE |
| 336 | 7 | _ | |2 ORCID |a JOURNAL_ARTICLE |
| 336 | 7 | _ | |0 0 |2 EndNote |a Journal Article |
| 500 | _ | _ | |a #LA:C020# |
| 520 | _ | _ | |a Adipokines including leptin, adiponectin and resistin have been linked to risk of obesity-related cancers potentially through low-grade chronic inflammation pathways. We aimed to assess the role of post-diagnosis circulating adipokines on long-term prognosis in a prospective breast cancer cohort. Adipokines were measured in blood collected at baseline shortly after diagnosis (2002-2005) and at follow-up (2009) from 3112 breast cancer patients enrolled in the population-based MARIE study. Half of the patients had measurements at both time-points. All-cause mortality, breast cancer specific mortality and recurrences were ascertained up to June 2015 (11 years median follow-up). Associations with time-varying adipokine concentrations overall and stratified by estrogen and progesterone receptor (ERPR) were evaluated using adjusted proportional hazard regression. At baseline (n = 2700) and follow-up (n = 2027), median concentrations for leptin, adiponectin and resistin were 4.6 and 2.7 ng/ml, 24.4 and 30.0 mg/l, 15.4 and 26.2 ng/ml, respectively. After adjustment, there was no evidence for associations between adipokines and any outcome overall. In ERPR negative tumors, highest vs. lowest quintile of adiponectin was significantly associated with increased breast cancer specific mortality (HR 2.51, 95%CI 1.07-5.92). Overall, post-diagnosis adipokines were not associated with long-term outcomes after breast cancer. In patients with ERPR negative tumors, higher concentrations of adiponectin may be associated with increased breast cancer specific mortality and warrant further investigation. |
| 536 | _ | _ | |0 G:(DE-HGF)POF4-313 |a 313 - Krebsrisikofaktoren und Prävention (POF4-313) |c POF4-313 |f POF IV |x 0 |
| 588 | _ | _ | |a Dataset connected to CrossRef, PubMed, , Journals: inrepo01.inet.dkfz-heidelberg.de |
| 700 | 1 | _ | |0 P:(DE-He78)bce1fdec5ce564e2666156d96aeabec9 |a Jung, Audrey Y |b 1 |u dkfz |
| 700 | 1 | _ | |a Maurer, Tabea |b 2 |
| 700 | 1 | _ | |a Huebner, Marianne |b 3 |
| 700 | 1 | _ | |0 P:(DE-He78)79ab945544e5bc017a2317b6146ed3aa |a Johnson, Theron |b 4 |u dkfz |
| 700 | 1 | _ | |0 P:(DE-He78)6b04712f3afe72044d496a25505cb1ea |a Behrens, Sabine |b 5 |u dkfz |
| 700 | 1 | _ | |0 P:(DE-He78)e16e2a17f7dd2e7f7e917c0382f19b2d |a Jaskulski, Stefanie |b 6 |
| 700 | 1 | _ | |a Becher, Heiko |b 7 |
| 700 | 1 | _ | |0 P:(DE-He78)c259d6cc99edf5c7bc7ce22c7f87c253 |a Chang-Claude, Jenny |b 8 |e Last author |u dkfz |
| 773 | _ | _ | |0 PERI:(DE-600)2615211-3 |a 10.1038/s41598-021-02958-w |g Vol. 11, no. 1, p. 23526 |n 1 |p 23526 |t Scientific reports |v 11 |x 2045-2322 |y 2021 |
| 909 | C | O | |o oai:inrepo02.dkfz.de:178415 |p VDB |
| 910 | 1 | _ | |0 I:(DE-588b)2036810-0 |6 P:(DE-He78)bce1fdec5ce564e2666156d96aeabec9 |a Deutsches Krebsforschungszentrum |b 1 |k DKFZ |
| 910 | 1 | _ | |0 I:(DE-588b)2036810-0 |6 P:(DE-He78)79ab945544e5bc017a2317b6146ed3aa |a Deutsches Krebsforschungszentrum |b 4 |k DKFZ |
| 910 | 1 | _ | |0 I:(DE-588b)2036810-0 |6 P:(DE-He78)6b04712f3afe72044d496a25505cb1ea |a Deutsches Krebsforschungszentrum |b 5 |k DKFZ |
| 910 | 1 | _ | |0 I:(DE-588b)2036810-0 |6 P:(DE-He78)e16e2a17f7dd2e7f7e917c0382f19b2d |a Deutsches Krebsforschungszentrum |b 6 |k DKFZ |
| 910 | 1 | _ | |0 I:(DE-588b)2036810-0 |6 P:(DE-He78)c259d6cc99edf5c7bc7ce22c7f87c253 |a Deutsches Krebsforschungszentrum |b 8 |k DKFZ |
| 913 | 1 | _ | |0 G:(DE-HGF)POF4-313 |1 G:(DE-HGF)POF4-310 |2 G:(DE-HGF)POF4-300 |3 G:(DE-HGF)POF4 |4 G:(DE-HGF)POF |a DE-HGF |b Gesundheit |l Krebsforschung |v Krebsrisikofaktoren und Prävention |x 0 |
| 914 | 1 | _ | |y 2021 |
| 915 | _ | _ | |0 StatID:(DE-HGF)0100 |2 StatID |a JCR |b SCI REP-UK : 2019 |d 2021-02-03 |
| 915 | _ | _ | |0 StatID:(DE-HGF)0200 |2 StatID |a DBCoverage |b SCOPUS |d 2021-02-03 |
| 915 | _ | _ | |0 StatID:(DE-HGF)0300 |2 StatID |a DBCoverage |b Medline |d 2021-02-03 |
| 915 | _ | _ | |0 StatID:(DE-HGF)0320 |2 StatID |a DBCoverage |b PubMed Central |d 2021-02-03 |
| 915 | _ | _ | |0 StatID:(DE-HGF)0501 |2 StatID |a DBCoverage |b DOAJ Seal |d 2021-02-03 |
| 915 | _ | _ | |0 StatID:(DE-HGF)0500 |2 StatID |a DBCoverage |b DOAJ |d 2021-02-03 |
| 915 | _ | _ | |0 StatID:(DE-HGF)0030 |2 StatID |a Peer Review |b DOAJ : Blind peer review |d 2021-02-03 |
| 915 | _ | _ | |0 LIC:(DE-HGF)CCBYNV |2 V:(DE-HGF) |a Creative Commons Attribution CC BY (No Version) |b DOAJ |d 2021-02-03 |
| 915 | _ | _ | |0 StatID:(DE-HGF)0600 |2 StatID |a DBCoverage |b Ebsco Academic Search |d 2021-02-03 |
| 915 | _ | _ | |0 StatID:(DE-HGF)0030 |2 StatID |a Peer Review |b ASC |d 2021-02-03 |
| 915 | _ | _ | |0 StatID:(DE-HGF)0199 |2 StatID |a DBCoverage |b Clarivate Analytics Master Journal List |d 2021-02-03 |
| 915 | _ | _ | |0 StatID:(DE-HGF)0160 |2 StatID |a DBCoverage |b Essential Science Indicators |d 2021-02-03 |
| 915 | _ | _ | |0 StatID:(DE-HGF)1050 |2 StatID |a DBCoverage |b BIOSIS Previews |d 2021-02-03 |
| 915 | _ | _ | |0 StatID:(DE-HGF)1150 |2 StatID |a DBCoverage |b Current Contents - Physical, Chemical and Earth Sciences |d 2021-02-03 |
| 915 | _ | _ | |0 StatID:(DE-HGF)1040 |2 StatID |a DBCoverage |b Zoological Record |d 2021-02-03 |
| 915 | _ | _ | |0 StatID:(DE-HGF)1190 |2 StatID |a DBCoverage |b Biological Abstracts |d 2021-02-03 |
| 915 | _ | _ | |0 StatID:(DE-HGF)0113 |2 StatID |a WoS |b Science Citation Index Expanded |d 2021-02-03 |
| 915 | _ | _ | |0 StatID:(DE-HGF)0150 |2 StatID |a DBCoverage |b Web of Science Core Collection |d 2021-02-03 |
| 915 | _ | _ | |0 StatID:(DE-HGF)9900 |2 StatID |a IF < 5 |d 2021-02-03 |
| 915 | _ | _ | |0 StatID:(DE-HGF)0561 |2 StatID |a Article Processing Charges |d 2021-02-03 |
| 915 | _ | _ | |0 StatID:(DE-HGF)0700 |2 StatID |a Fees |d 2021-02-03 |
| 920 | 1 | _ | |0 I:(DE-He78)C020-20160331 |k C020 |l C020 Epidemiologie von Krebs |x 0 |
| 980 | _ | _ | |a journal |
| 980 | _ | _ | |a VDB |
| 980 | _ | _ | |a I:(DE-He78)C020-20160331 |
| 980 | _ | _ | |a UNRESTRICTED |
| Library | Collection | CLSMajor | CLSMinor | Language | Author |
|---|