000178446 001__ 178446 000178446 005__ 20240229143547.0 000178446 0247_ $$2doi$$a10.2196/25440 000178446 0247_ $$2pmid$$apmid:35014967 000178446 0247_ $$2ISSN$$a1438-8871 000178446 0247_ $$2ISSN$$a1439-4456 000178446 0247_ $$2altmetric$$aaltmetric:120661656 000178446 037__ $$aDKFZ-2022-00072 000178446 041__ $$aEnglish 000178446 082__ $$a610 000178446 1001_ $$00000-0002-8349-6798$$aUlrich, Hannes$$b0 000178446 245__ $$aUnderstanding the Nature of Metadata: Systematic Review. 000178446 260__ $$aRichmond, Va.$$bHealthcare World$$c2022 000178446 3367_ $$2DRIVER$$aarticle 000178446 3367_ $$2DataCite$$aOutput Types/Journal article 000178446 3367_ $$0PUB:(DE-HGF)16$$2PUB:(DE-HGF)$$aJournal Article$$bjournal$$mjournal$$s1642060375_472$$xReview Article 000178446 3367_ $$2BibTeX$$aARTICLE 000178446 3367_ $$2ORCID$$aJOURNAL_ARTICLE 000178446 3367_ $$00$$2EndNote$$aJournal Article 000178446 520__ $$aMetadata are created to describe the corresponding data in a detailed and unambiguous way and is used for various applications in different research areas, for example, data identification and classification. However, a clear definition of metadata is crucial for further use. Unfortunately, extensive experience with the processing and management of metadata has shown that the term 'metadata' and its use is not always unambiguous.This study aimed to understand the definition of metadata and the challenges resulting from metadata reuse.A systematic literature search was performed in this study following the PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) guidelines for reporting on systematic reviews. Five research questions were identified to streamline the review process, addressing metadata characteristics, metadata standards, use cases, and problems encountered. This review was preceded by a harmonization process to achieve a general understanding of the terms used.The harmonization process resulted in a clear set of definitions for metadata processing focusing on data integration. The following literature review was conducted by 10 reviewers with different backgrounds and using the harmonized definitions. This study included 81 peer-reviewed papers from the last decade after applying various filtering steps to identify the most relevant papers. The 5 research questions could be answered, resulting in a broad overview of the standards, use cases, problems, and corresponding solutions for the application of metadata in different research areas.Metadata can be a powerful tool for identifying, describing, and processing information, but its meaningful creation is costly and challenging. This review process uncovered many standards, use cases, problems, and solutions for dealing with metadata. The presented harmonized definitions and the new schema have the potential to improve the classification and generation of metadata by creating a shared understanding of metadata and its context. 000178446 536__ $$0G:(DE-HGF)POF4-315$$a315 - Bildgebung und Radioonkologie (POF4-315)$$cPOF4-315$$fPOF IV$$x0 000178446 588__ $$aDataset connected to CrossRef, PubMed, , Journals: inrepo01.inet.dkfz-heidelberg.de 000178446 650_7 $$2Other$$adata classification 000178446 650_7 $$2Other$$adata identification 000178446 650_7 $$2Other$$adata integration 000178446 650_7 $$2Other$$ametadata 000178446 650_7 $$2Other$$ametadata definition 000178446 650_7 $$2Other$$asystematic review 000178446 7001_ $$00000-0001-6685-4429$$aKock-Schoppenhauer, Ann-Kristin$$b1 000178446 7001_ $$00000-0002-8031-1209$$aDeppenwiese, Noemi$$b2 000178446 7001_ $$00000-0001-9985-8311$$aGött, Robert$$b3 000178446 7001_ $$0P:(DE-He78)a2a7355881803969298582b28c64c64a$$aKern, Jori$$b4$$udkfz 000178446 7001_ $$0P:(DE-He78)e4ad7b4e684492de43cfcb12e5397439$$aLablans, Martin$$b5$$udkfz 000178446 7001_ $$00000-0002-8260-8815$$aMajeed, Raphael W$$b6 000178446 7001_ $$00000-0002-3628-7280$$aStöhr, Mark R$$b7 000178446 7001_ $$00000-0003-0348-5579$$aStausberg, Jürgen$$b8 000178446 7001_ $$00000-0002-7206-3719$$aVarghese, Julian$$b9 000178446 7001_ $$00000-0001-9740-0788$$aDugas, Martin$$b10 000178446 7001_ $$00000-0002-3274-8422$$aIngenerf, Josef$$b11 000178446 773__ $$0PERI:(DE-600)2028830-X$$a10.2196/25440$$gVol. 24, no. 1, p. e25440 -$$n1$$pe25440$$tJournal of medical internet research$$v24$$x1438-8871$$y2022 000178446 909CO $$ooai:inrepo02.dkfz.de:178446$$pVDB 000178446 9101_ $$0I:(DE-588b)2036810-0$$6P:(DE-He78)a2a7355881803969298582b28c64c64a$$aDeutsches Krebsforschungszentrum$$b4$$kDKFZ 000178446 9101_ $$0I:(DE-588b)2036810-0$$6P:(DE-He78)e4ad7b4e684492de43cfcb12e5397439$$aDeutsches Krebsforschungszentrum$$b5$$kDKFZ 000178446 9131_ $$0G:(DE-HGF)POF4-315$$1G:(DE-HGF)POF4-310$$2G:(DE-HGF)POF4-300$$3G:(DE-HGF)POF4$$4G:(DE-HGF)POF$$aDE-HGF$$bGesundheit$$lKrebsforschung$$vBildgebung und Radioonkologie$$x0 000178446 9141_ $$y2022 000178446 915__ $$0LIC:(DE-HGF)CCBYNV$$2V:(DE-HGF)$$aCreative Commons Attribution CC BY (No Version)$$bDOAJ$$d2021-01-29 000178446 915__ $$0StatID:(DE-HGF)0160$$2StatID$$aDBCoverage$$bEssential Science Indicators$$d2021-01-29 000178446 915__ $$0StatID:(DE-HGF)0113$$2StatID$$aWoS$$bScience Citation Index Expanded$$d2021-01-29 000178446 915__ $$0StatID:(DE-HGF)0561$$2StatID$$aArticle Processing Charges$$d2021-01-29 000178446 915__ $$0StatID:(DE-HGF)0562$$2StatID$$aSubmission fee$$d2021-01-29 000178446 915__ $$0StatID:(DE-HGF)0700$$2StatID$$aFees$$d2021-01-29 000178446 915__ $$0StatID:(DE-HGF)0100$$2StatID$$aJCR$$bJ MED INTERNET RES : 2021$$d2022-11-30 000178446 915__ $$0StatID:(DE-HGF)0200$$2StatID$$aDBCoverage$$bSCOPUS$$d2022-11-30 000178446 915__ $$0StatID:(DE-HGF)0300$$2StatID$$aDBCoverage$$bMedline$$d2022-11-30 000178446 915__ $$0StatID:(DE-HGF)0501$$2StatID$$aDBCoverage$$bDOAJ Seal$$d2021-04-01T12:45:48Z 000178446 915__ $$0StatID:(DE-HGF)0500$$2StatID$$aDBCoverage$$bDOAJ$$d2021-04-01T12:45:48Z 000178446 915__ $$0StatID:(DE-HGF)0030$$2StatID$$aPeer Review$$bDOAJ : Peer review$$d2021-04-01T12:45:48Z 000178446 915__ $$0StatID:(DE-HGF)0199$$2StatID$$aDBCoverage$$bClarivate Analytics Master Journal List$$d2022-11-30 000178446 915__ $$0StatID:(DE-HGF)0150$$2StatID$$aDBCoverage$$bWeb of Science Core Collection$$d2022-11-30 000178446 915__ $$0StatID:(DE-HGF)1110$$2StatID$$aDBCoverage$$bCurrent Contents - Clinical Medicine$$d2022-11-30 000178446 915__ $$0StatID:(DE-HGF)9905$$2StatID$$aIF >= 5$$bJ MED INTERNET RES : 2021$$d2022-11-30 000178446 9201_ $$0I:(DE-He78)E260-20160331$$kE260$$lVerbundinformationssysteme$$x0 000178446 980__ $$ajournal 000178446 980__ $$aVDB 000178446 980__ $$aI:(DE-He78)E260-20160331 000178446 980__ $$aUNRESTRICTED