%0 Journal Article
%A Lam, Suk Yee
%A Mommersteeg, Michiel C
%A Yu, Bingting
%A Broer, Linda
%A Spaander, Manon C W
%A Frost, Fabian
%A Weiss, Stefan
%A Völzke, Henry
%A Lerch, Markus M
%A Schöttker, Ben
%A Zhang, Yan
%A Stocker, Hannah
%A Brenner, Hermann
%A Levy, Daniel
%A Hwang, Shih-Jen
%A Wood, Alexis C
%A Rich, Stephen S
%A Rotter, Jerome I
%A Taylor, Kent D
%A Tracy, Russell P
%A Kabagambe, Edmond K
%A Leja, Marcis
%A Klovins, Janis
%A Peculis, Raitis
%A Rudzite, Dace
%A Nikitina-Zake, Liene
%A Skenders, Girts
%A Rovite, Vita
%A Uitterlinden, André
%A Kuipers, Ernst J
%A Fuhler, Gwenny M
%A Homuth, Georg
%A Peppelenbosch, Maikel P
%T Toll-like receptor 1 locus re-examined in a genome-wide association study update on anti-Helicobacter pylori IgG titers.
%J Gastroenterology
%V 162
%N 6
%@ 0016-5085
%C Philadelphia, Pa. [u.a.]
%I Saunders
%M DKFZ-2022-00121
%P 1705-1715
%D 2022
%Z 2022 May;162(6):1705-1715
%X A genome-wide significant association between anti-Helicobacter pylori (H. pylori) IgG titers and Toll-like receptor (TLR1/6/10) locus on 4p14 was demonstrated for individuals of European ancestry, but not uniformly replicated. We re-investigate this association in an updated genome-wide association study (GWAS) meta-analysis for low gastric cancer incidence populations, address potential causes of cohort heterogeneity and explore functional implications of genetic variation at the TLR1/6/10 locus.The dichotomous GWAS (25
%K Polymorphism (Other)
%K Single Nucleotide (Other)
%K bacteria (Other)
%K immunity (Other)
%K serology (Other)
%F PUB:(DE-HGF)16
%9 Journal Article
%$ pmid:35031300
%R 10.1053/j.gastro.2022.01.011
%U https://inrepo02.dkfz.de/record/178524