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000178738 041__ $$aEnglish
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000178738 1001_ $$0P:(DE-He78)e9acc181eadf1c41b9a43639fc1c9faf$$aSchlehofer, Brigitte$$b0$$eFirst author
000178738 245__ $$aAssociation of allergic diseases and epilepsy with risk of glioma, meningioma and acoustic neuroma: results from the INTERPHONE international case-control study.
000178738 260__ $$aDordrecht [u.a.]$$bSpringer Science + Business Media B.V.$$c2022
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000178738 500__ $$a#EA:C030# / 2022 May;37(5):503-512
000178738 520__ $$aWe investigated the association of allergic diseases and epilepsy with risk of brain tumours, in Interphone, a 13-country case-control study. Data were obtained from 2693 glioma cases, 2396 meningioma cases, and 1102 acoustic neuroma cases and their 6321 controls. Conditional logistic regression models were used to estimate pooled odds ratios (ORs) and their respective 95% confidence intervals (CIs), adjusted for education and time at interview. Reduced ORs were observed for glioma in relation to physician-diagnosed asthma (OR = 0.73; CI 0.58-0.92), hay fever (OR 0.72; CI 0.61-0.86), and eczema (OR 0.78, CI 0.64-0.94), but not for meningioma or acoustic neuroma. Previous diagnosis of epilepsy was associated with an increased OR for glioma (2.94; CI 1.87-4.63) and for meningioma (2.12; CI 1.27-3.56), but not for acoustic neuroma. This large-scale case-control study adds to the growing evidence that people with allergies have a lower risk of developing glioma, but not meningioma or acoustic neuroma. It also supports clinical observations of epilepsy prior to the diagnosis of glioma and meningioma.
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000178738 650_7 $$2Other$$aAllergies
000178738 650_7 $$2Other$$aBrain tumours
000178738 650_7 $$2Other$$aEpilepsy
000178738 650_7 $$2Other$$aMulticenter case–control study
000178738 7001_ $$aBlettner, Maria$$b1
000178738 7001_ $$aMoissonnier, Monika$$b2
000178738 7001_ $$00000-0002-6602-6292$$aDeltour, Isabelle$$b3
000178738 7001_ $$00000-0003-4946-9099$$aGiles, Graham G$$b4
000178738 7001_ $$aArmstrong, Bruce$$b5
000178738 7001_ $$00000-0002-9042-8582$$aSiemiatycki, Jack$$b6
000178738 7001_ $$00000-0002-4196-3773$$aParent, Marie-Elise$$b7
000178738 7001_ $$aKrewski, Daniel$$b8
000178738 7001_ $$aJohansen, Christoffer$$b9
000178738 7001_ $$00000-0003-1125-4818$$aAuvinen, Anssi$$b10
000178738 7001_ $$aLahkola, Anna$$b11
000178738 7001_ $$aHours, Martine$$b12
000178738 7001_ $$00000-0003-1614-938X$$aBerg-Beckhoff, Gabriele$$b13
000178738 7001_ $$aSadetzki, Siegal$$b14
000178738 7001_ $$00000-0001-8883-8745$$aLagorio, Susanna$$b15
000178738 7001_ $$aTakebayashi, Toru$$b16
000178738 7001_ $$aYamaguchi, Naohito$$b17
000178738 7001_ $$aWoodward, Alistair$$b18
000178738 7001_ $$aCook, Angus$$b19
000178738 7001_ $$aTynes, Tore$$b20
000178738 7001_ $$aKlaboe, Lars$$b21
000178738 7001_ $$00000-0002-5101-0060$$aFeychting, Maria$$b22
000178738 7001_ $$aFeltbower, Richard$$b23
000178738 7001_ $$aSwerdlow, Anthony$$b24
000178738 7001_ $$aSchoemaker, Minouk$$b25
000178738 7001_ $$00000-0003-0999-6839$$aCardis, Elisabeth$$b26
000178738 7001_ $$00000-0001-9687-2134$$aSchüz, Joachim$$b27
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