%0 Journal Article
%A Spurny, Manuela
%A Jiang, Yixin
%A Sowah, Solomon
%A Nonnenmacher, Tobias
%A Schübel, Ruth
%A Kirsten, Romy
%A Johnson, Theron
%A von Stackelberg, Oyunbileg
%A Ulrich, Cornelia M
%A Kaaks, Rudolf
%A Kauczor, Hans-Ulrich
%A Kühn, Tilman
%A Nattenmüller, Johanna
%T Changes in Kidney Fat upon Dietary-Induced Weight Loss.
%J Nutrients
%V 14
%N 7
%@ 2072-6643
%C Basel
%I MDPI
%M DKFZ-2022-00730
%P 1437
%D 2022
%X As the metabolic role of kidney fat remains unclear, we investigated the effects of dietary weight loss on kidney fat content (KFC) and its connection to kidney function and metabolism. Overweight or obese participants (n = 137) of a dietary intervention trial were classified into quartiles of weight loss in a post hoc manner. Kidney sinus (KSF) and cortex fat (KCF) were measured by magnetic resonance imaging at baseline, week 12 and week 50. Weight loss effects on KFC were evaluated by linear mixed models. Repeated measures correlations between KFC, other body fat measures and metabolic biomarkers were obtained. KSF, but not KCF, decreased significantly across weight loss quartiles at week 12 (quartile 4: -21.3
%K Adipose Tissue: metabolism
%K Biomarkers
%K Humans
%K Kidney: metabolism
%K Obesity: metabolism
%K Overweight: complications
%K Weight Loss: physiology
%K body composition (Other)
%K diet induced weight loss (Other)
%K kidney fat content (Other)
%K magnetic resonance imaging (Other)
%K obesity (Other)
%K overweight (Other)
%K renal sinus fat (Other)
%K Biomarkers (NLM Chemicals)
%F PUB:(DE-HGF)16
%9 Journal Article
%$ pmid:35406052
%2 pmc:PMC9002806
%R 10.3390/nu14071437
%U https://inrepo02.dkfz.de/record/179552