TY  - JOUR
AU  - Hemminki, Kari
AU  - Kanerva, Anna
AU  - Försti, Asta
AU  - Hemminki, Akseli
TI  - Cervical, vaginal and vulvar cancer incidence and survival trends in Denmark, Finland, Norway and Sweden with implications to treatment.
JO  - BMC cancer
VL  - 22
IS  - 1
SN  - 1471-2407
CY  - Heidelberg
PB  - Springer
M1  - DKFZ-2022-00863
SP  - 456
PY  - 2022
AB  - Incidence of cervical cancer has been reduced by organized screening while for vaginal and vulvar cancers no systematic screening has been implemented. All these cancers are associated with human papilloma virus (HPV) infection. We wanted to analyze incidence trends and relative survival in these cancers with specific questions about the possible covariation of incidence, survival changes coinciding with incidence changes and the role of treatment in survival. We used nationwide cancer registry data for Denmark (DK), Finland (FI), Norway (NO) and Sweden (SE) to address these questions.We use the NORDCAN database for the analyses: incidence data were available from 1943 in DK, 1953 in FI and NO and 1960 in SE, through 2016. Survival data were available from 1967 through 2016. World standard population was used in age standardization.In each country the incidence of cervical cancer declined subsequent to rolling out of screening activities. The attained plateau incidence was lowest at 4/100,000 in FI and highest at 10/100,000 in DK and NO. The incidence of vaginal and vulvar cancer remained relatively constant at about 2/100,000. Relative 1-year survival in cervical cancer improved in all countries from low 80
KW  - Denmark: epidemiology
KW  - Early Detection of Cancer
KW  - Female
KW  - Finland: epidemiology
KW  - Humans
KW  - Incidence
KW  - Middle Aged
KW  - Norway: epidemiology
KW  - Papillomavirus Infections
KW  - Sweden: epidemiology
KW  - Uterine Cervical Neoplasms: prevention & control
KW  - Uterine Cervical Neoplasms: therapy
KW  - Vulvar Neoplasms: epidemiology
KW  - Vulvar Neoplasms: therapy
KW  - Age-specific incidence (Other)
KW  - Human papilloma virus (Other)
KW  - Incidence trends (Other)
KW  - Relative survival (Other)
KW  - Risk factors (Other)
LB  - PUB:(DE-HGF)16
C6  - pmid:35473606
DO  - DOI:10.1186/s12885-022-09582-5
UR  - https://inrepo02.dkfz.de/record/179731
ER  -