%0 Journal Article
%A Lopez, Cristina
%A Schleussner, Nikolai
%A Bernhart, Stephan H
%A Kleinheinz, Kortine
%A Sungalee, Stephanie
%A Sczakiel, Henrike L
%A Kretzmer, Helene
%A Toprak, Umut H
%A Glaser, Selina
%A Wagener, Rabea
%A Ammerpohl, Ole
%A Bens, Susanne
%A Giefing, Maciej
%A Sanchez, Juan C Gonzalez
%A Apic, Gordana
%A Hubschmann, Daniel
%A Janz, Martin
%A Kreuz, Markus
%A Mottok, Anja
%A Muller, Judith M
%A Seufert, Julian
%A Hoffmann, Steve
%A Korbel, Jan O
%A Russell, Robert B
%A Schule, Roland
%A Trumper, Lorenz
%A Klapper, Wolfram
%A Radlwimmer, Bernhard
%A Lichter, Peter
%A Kuppers, Ralf
%A Schlesner, Matthias
%A Mathas, Stephan
%A Siebert, Reiner
%T Focal structural variants revealed by whole genome sequencing disrupt the histone demethylase KDM4C in B cell lymphomas.
%J Haematologica
%V 108
%N 2
%@ 0390-6078
%C Pavia
%I Ferrata Storti Foundation
%M DKFZ-2022-00924
%P 543-554
%D 2023
%Z 2023 Feb 1;108(2):543-554
%X Histone methylation-modifiers, like EZH2 and KMT2D, are recurrently altered in B-cell lymphomas. To comprehensively describe the landscape of alterations affecting genes encoding histone methylation-modifiers in lymphomagenesis we investigated whole genome and transcriptome data of 186 mature B-cell lymphomas sequenced in the ICGC MMML-Seq project. Besides confirming common alterations of KMT2D (47
%F PUB:(DE-HGF)16
%9 Journal Article
%$ pmid:35522148
%R 10.3324/haematol.2021.280005
%U https://inrepo02.dkfz.de/record/179850