TY  - JOUR
AU  - Lopez, Cristina
AU  - Schleussner, Nikolai
AU  - Bernhart, Stephan H
AU  - Kleinheinz, Kortine
AU  - Sungalee, Stephanie
AU  - Sczakiel, Henrike L
AU  - Kretzmer, Helene
AU  - Toprak, Umut H
AU  - Glaser, Selina
AU  - Wagener, Rabea
AU  - Ammerpohl, Ole
AU  - Bens, Susanne
AU  - Giefing, Maciej
AU  - Sanchez, Juan C Gonzalez
AU  - Apic, Gordana
AU  - Hubschmann, Daniel
AU  - Janz, Martin
AU  - Kreuz, Markus
AU  - Mottok, Anja
AU  - Muller, Judith M
AU  - Seufert, Julian
AU  - Hoffmann, Steve
AU  - Korbel, Jan O
AU  - Russell, Robert B
AU  - Schule, Roland
AU  - Trumper, Lorenz
AU  - Klapper, Wolfram
AU  - Radlwimmer, Bernhard
AU  - Lichter, Peter
AU  - Kuppers, Ralf
AU  - Schlesner, Matthias
AU  - Mathas, Stephan
AU  - Siebert, Reiner
TI  - Focal structural variants revealed by whole genome sequencing disrupt the histone demethylase KDM4C in B cell lymphomas.
JO  - Haematologica
VL  - 108
IS  - 2
SN  - 0390-6078
CY  - Pavia
PB  - Ferrata Storti Foundation
M1  - DKFZ-2022-00924
SP  - 543-554
PY  - 2023
N1  - 2023 Feb 1;108(2):543-554
AB  - Histone methylation-modifiers, like EZH2 and KMT2D, are recurrently altered in B-cell lymphomas. To comprehensively describe the landscape of alterations affecting genes encoding histone methylation-modifiers in lymphomagenesis we investigated whole genome and transcriptome data of 186 mature B-cell lymphomas sequenced in the ICGC MMML-Seq project. Besides confirming common alterations of KMT2D (47
LB  - PUB:(DE-HGF)16
C6  - pmid:35522148
DO  - DOI:10.3324/haematol.2021.280005
UR  - https://inrepo02.dkfz.de/record/179850
ER  -