TY  - JOUR
AU  - Eichkorn, Tanja
AU  - Bauer, Julia
AU  - Bahn, Emanuel
AU  - Lischalk, Jonathan W
AU  - Meixner, Eva
AU  - Sandrini, Elisabetta
AU  - Regnery, Sebastian
AU  - Held, Thomas
AU  - Hörner-Rieber, Juliane
AU  - Alber, Markus
AU  - Herfarth, Klaus
AU  - Debus, Jürgen
AU  - König, Laila
AU  - Harrabi, Semi
TI  - Radiation-induced contrast enhancement following proton radiotherapy for low-grade glioma depends on tumor characteristics and is rarer in children than adults.
JO  - Radiotherapy and oncology
VL  - 172
SN  - 0167-8140
CY  - Amsterdam [u.a.]
PB  - Elsevier Science
M1  - DKFZ-2022-00981
SP  -  54-64
PY  - 2022
N1  - Volume 172, July 2022, Pages 54-64
AB  - Proton beam radiotherapy (PRT) is used in the treatment of low-grade glioma (LGG) to mitigate long-term sequelae. Following PRT, increased rates of radiation-induced contrast enhancements (RICE) are suspected but poorly understood.We analyzed consecutive 227 patients (42 children and 185 adults) treated with PRT (54Gy RBE) for LGG from 2010 to 2020 and followed with serial clinical exams and magnetic resonance imaging for in median 5.6 years.Tumors were graded WHO 1 in a minority (n = 22, 12
KW  - Low-grade glioma (Other)
KW  - Pediatrics (Other)
KW  - Proton radiotherapy (Other)
KW  - Pseudoprogression/Radiation necrosis (Other)
KW  - Radiation-induced contrast enhancements (RICE) (Other)
LB  - PUB:(DE-HGF)16
C6  - pmid:35568281
DO  - DOI:10.1016/j.radonc.2022.05.005
UR  - https://inrepo02.dkfz.de/record/179932
ER  -