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@ARTICLE{Klotz:179959,
      author       = {R. Klotz and M. Holze and C. Dörr-Harim and E. Grohmann
                      and B. Nied and B. Lebert and S. Weg-Remers$^*$ and C. Lutz
                      and K. Meißler and P. Schloss and C. Ullrich and S.
                      Frankenhauser and H. Lutter and D. Bühler and A. Ahmed and
                      T. Gronlund and A. L. Mihaljevic and A. Mihaljevic and R.
                      Klotz and C. Dörr-Harim and D. Bühler and C. Dörr-Harim
                      and S. Frankenhauser and S. Gapp-Frasch and E. Grohmann and
                      V. Helmstädter and C. Hey and W. Hey and R. Klotz and A.
                      Mihaljevic and B. Lebert and C. Lutz and H. Lutter and C.
                      Lutz and K. Meißler and B. Nied and P. Schloss and S.
                      Stegmüller and P. Stünzi and A. Trabold-Hauk and C.
                      Ullrich and S. Weg-Remers$^*$ and M. Wensing},
      collaboration = {F. Darmkrebs and S. G. F. D. S. C. Cancer},
      title        = {{T}op 10 research priorities in colorectal cancer: results
                      from the {C}olorectal {C}ancer {P}riority-{S}etting
                      {P}artnership.},
      journal      = {Journal of cancer research and clinical oncology},
      volume       = {149},
      number       = {4},
      issn         = {0171-5216},
      address      = {Berlin},
      publisher    = {Springer},
      reportid     = {DKFZ-2022-01008},
      pages        = {1561-1568},
      year         = {2023},
      note         = {2023 Apr;149(4):1561-1568},
      abstract     = {Colorectal cancer (CRC) is the third most frequent cause of
                      cancer death in the word. Which aspects of research into CRC
                      should be accorded the highest priority remains unclear,
                      because relevant stakeholders, such as patients, nurses, and
                      physicians, played hardly any part in the development of
                      research projects. The goal in forming the CRC
                      Priority-Setting Partnership (PSP) was to bring all relevant
                      stakeholders together to identify and prioritize unresolved
                      research questions regarding the diagnosis, treatment, and
                      follow-up of CRC.The CRC PSP worked in cooperation with the
                      British James Lind Alliance. An initial nationwide survey
                      was conducted, and evidence uncertainties were collected,
                      categorized, summarized, and compared with available
                      evidence from the literature. The as-yet unresolved
                      questions were (provisionally) ranked in a second national
                      wide survey, and at a concluding consensus workshop all
                      stakeholders came together to finalize the rankings in a
                      nominal group process and compile a top 10 list.In the first
                      survey $(34\%$ patients, $51\%$ healthcare professionals,
                      $15\%$ unknown), 1102 submissions were made. After exclusion
                      of duplicates and previously resolved questions, 66 topics
                      were then ranked in the second survey $(56\%$ patients,
                      $39\%$ healthcare professionals, $5\%$ unknown). This
                      interim ranking process revealed distinct differences
                      between relatives and healthcare professionals. The final
                      top 10 list compiled at the consensus workshop covers a wide
                      area of research topics.All relevant stakeholders in the CRC
                      PSP worked together to identify and prioritize the top 10
                      evidence uncertainties. The results give researchers and
                      funding bodies the opportunity to address the most
                      patient-relevant research projects. It is the first detailed
                      description of a PSP in Germany, and the first PSP on CRC
                      care worldwide.},
      keywords     = {Colorectal neoplasms (Other) / Forschungspartnerschaft
                      (Other) / Patient participation (Other) / Priority-Setting
                      Partnership (Other)},
      cin          = {M100},
      ddc          = {610},
      cid          = {I:(DE-He78)M100-20160331},
      pnm          = {313 - Krebsrisikofaktoren und Prävention (POF4-313)},
      pid          = {G:(DE-HGF)POF4-313},
      typ          = {PUB:(DE-HGF)16},
      pubmed       = {pmid:35579718},
      doi          = {10.1007/s00432-022-04042-w},
      url          = {https://inrepo02.dkfz.de/record/179959},
}