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000180272 1001_ $$0P:(DE-He78)2def8f8594c8f797f5ed4398258c6cac$$aSchmidt, Martina$$b0$$eFirst author$$udkfz
000180272 245__ $$aLate effects, long-term problems and unmet needs of cancer survivors.
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000180272 500__ $$a#EA:C110#LA:C110# / 2022 Oct 15;151(8):1280-1290
000180272 520__ $$aGreat efforts are being made in cancer treatment, with impressive improvement in survival. The situation concerning research and care for long-term problems and late effects in the growing population of cancer survivors, however, is unsatisfactory. Therefore, in the FiX survey 1,348 disease-free survivors about 4 years after diagnosis of different cancer types were asked to rate existing burdens and support received for them along a list of 36 potential problems. Health-related quality of life (HRQoL) was assessed with the EORTC QLQ-C30. Determinants of burdens were explored using logistic regression analysis. While cancer survivors' global HRQoL, physical and role function ratings were comparable or better than age- and sex-matched reference values of the general population, emotional and cognitive function was worse, especially among women (p<.01). Most frequently reported problems with at least moderate burden were loss of physical performance (36.3%), fatigue (35.1%), sexual problems (34.7%), sleep problems (34,1%), arthralgia (33.8%), anxiety (28.0%), neuropathy (25.6%), memory problems (23.0%) and concentration problems (21.9%). Burdened survivors often rated received support as poor, especially regarding support for problems that physicians might consider medically non-threatening, or for which no effective pharmacologic or medical treatment is known. Determinants for burden included higher age, female gender, having ever received chemotherapy and overweight/obesity. In conclusion, a significant number of cancer survivors suffer from long-term or late effects and have unmet care needs. Awareness of health care professionals should be increased for these issues. The results of our study can contribute to the development of targeted survivorship plans. This article is protected by copyright. All rights reserved.
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000180272 650_7 $$2Other$$acancer survivorship
000180272 650_7 $$2Other$$apatient-reported outcomes
000180272 650_7 $$2Other$$aquality of life
000180272 650_7 $$2Other$$asupportive care
000180272 7001_ $$0P:(DE-He78)f42e2297e771e17df08f2cc1171df9e4$$aGoldschmidt, Siri$$b1$$udkfz
000180272 7001_ $$0P:(DE-He78)a8ce1da94e91296e574e4849cfabd230$$aHermann, Silke$$b2$$udkfz
000180272 7001_ $$0P:(DE-He78)a0c2037d9054be26907a05ae520d5756$$aSteindorf, Karen$$b3$$eLast author$$udkfz
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