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@ARTICLE{Schmidt:180272,
author = {M. Schmidt$^*$ and S. Goldschmidt$^*$ and S. Hermann$^*$
and K. Steindorf$^*$},
title = {{L}ate effects, long-term problems and unmet needs of
cancer survivors.},
journal = {International journal of cancer},
volume = {151},
number = {8},
issn = {0020-7136},
address = {Bognor Regis},
publisher = {Wiley-Liss},
reportid = {DKFZ-2022-01218},
pages = {1280-1290},
year = {2022},
note = {#EA:C110#LA:C110# / 2022 Oct 15;151(8):1280-1290},
abstract = {Great efforts are being made in cancer treatment, with
impressive improvement in survival. The situation concerning
research and care for long-term problems and late effects in
the growing population of cancer survivors, however, is
unsatisfactory. Therefore, in the FiX survey 1,348
disease-free survivors about 4 years after diagnosis of
different cancer types were asked to rate existing burdens
and support received for them along a list of 36 potential
problems. Health-related quality of life (HRQoL) was
assessed with the EORTC QLQ-C30. Determinants of burdens
were explored using logistic regression analysis. While
cancer survivors' global HRQoL, physical and role function
ratings were comparable or better than age- and sex-matched
reference values of the general population, emotional and
cognitive function was worse, especially among women
(p<.01). Most frequently reported problems with at least
moderate burden were loss of physical performance
$(36.3\%),$ fatigue $(35.1\%),$ sexual problems $(34.7\%),$
sleep problems $(34,1\%),$ arthralgia $(33.8\%),$ anxiety
$(28.0\%),$ neuropathy $(25.6\%),$ memory problems
$(23.0\%)$ and concentration problems $(21.9\%).$ Burdened
survivors often rated received support as poor, especially
regarding support for problems that physicians might
consider medically non-threatening, or for which no
effective pharmacologic or medical treatment is known.
Determinants for burden included higher age, female gender,
having ever received chemotherapy and overweight/obesity. In
conclusion, a significant number of cancer survivors suffer
from long-term or late effects and have unmet care needs.
Awareness of health care professionals should be increased
for these issues. The results of our study can contribute to
the development of targeted survivorship plans. This article
is protected by copyright. All rights reserved.},
keywords = {cancer survivorship (Other) / patient-reported outcomes
(Other) / quality of life (Other) / supportive care (Other)},
cin = {C110 / M110},
ddc = {610},
cid = {I:(DE-He78)C110-20160331 / I:(DE-He78)M110-20160331},
pnm = {313 - Krebsrisikofaktoren und Prävention (POF4-313)},
pid = {G:(DE-HGF)POF4-313},
typ = {PUB:(DE-HGF)16},
pubmed = {pmid:35657637},
doi = {10.1002/ijc.34152},
url = {https://inrepo02.dkfz.de/record/180272},
}