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000180301 0247_ $$2ISSN$$a1433-0458
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000180301 037__ $$aDKFZ-2022-01228
000180301 041__ $$aGerman
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000180301 1001_ $$00000-0002-7307-484X$$aWeusthof, Katharina$$b0
000180301 245__ $$aRadiation therapy of malignant salivary gland tumors. [Strahlentherapie von malignen Speicheldrüsentumoren].
000180301 260__ $$aNew York$$bSpringer$$c2023
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000180301 500__ $$a2023 Apr;71(4):243-249
000180301 520__ $$aDue to their rarity, histologic heterogeneity, and localization, treatment of malignant salivary gland tumors requires an interdisciplinary approach. First-line treatment includes complete tumor resection. Postoperative radiation therapy is advised in patients with risk factors, i.e., incomplete tumor resection, high-grade tumors, or perineural invasion. Definitive radiation therapy is only advised for inoperable tumors because of significantly lower local control and survival rates when compared to combined surgery and radiation therapy. In radiation oncology, modern techniques such as intensity-modulated radiation therapy (IMRT) or particle therapy with heavy ions (i.e., C12) have led to improved outcomes in the treatment of head and neck tumors, especially of adenoid cystic carcinomas. Given the biological and physical benefits of particles, particle therapy, particularly carbon ion radiation, is a promising therapeutic approach for salivary gland tumors that will be further investigated in prospective clinical studies.
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000180301 650_7 $$2Other$$aCranial nerves
000180301 650_7 $$2Other$$aProton therapy
000180301 650_7 $$2Other$$aRadiotherapy
000180301 650_7 $$2Other$$aSalivary gland neoplasms
000180301 650_7 $$2Other$$aSkull base
000180301 7001_ $$0P:(DE-He78)8714da4e45acfa36ce87c291443a9218$$aDebus, Jürgen$$b1$$udkfz
000180301 7001_ $$aAdeberg, Sebastian$$b2
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