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@ARTICLE{Weusthof:180301,
      author       = {K. Weusthof and J. Debus$^*$ and S. Adeberg},
      title        = {{R}adiation therapy of malignant salivary gland tumors.
                      [{S}trahlentherapie von malignen {S}peicheldrüsentumoren].},
      journal      = {HNO},
      volume       = {71},
      number       = {4},
      issn         = {0017-6192},
      address      = {New York},
      publisher    = {Springer},
      reportid     = {DKFZ-2022-01228},
      pages        = {243-249},
      year         = {2023},
      note         = {2023 Apr;71(4):243-249},
      abstract     = {Due to their rarity, histologic heterogeneity, and
                      localization, treatment of malignant salivary gland tumors
                      requires an interdisciplinary approach. First-line treatment
                      includes complete tumor resection. Postoperative radiation
                      therapy is advised in patients with risk factors, i.e.,
                      incomplete tumor resection, high-grade tumors, or perineural
                      invasion. Definitive radiation therapy is only advised for
                      inoperable tumors because of significantly lower local
                      control and survival rates when compared to combined surgery
                      and radiation therapy. In radiation oncology, modern
                      techniques such as intensity-modulated radiation therapy
                      (IMRT) or particle therapy with heavy ions (i.e., C12) have
                      led to improved outcomes in the treatment of head and neck
                      tumors, especially of adenoid cystic carcinomas. Given the
                      biological and physical benefits of particles, particle
                      therapy, particularly carbon ion radiation, is a promising
                      therapeutic approach for salivary gland tumors that will be
                      further investigated in prospective clinical studies.},
      subtyp        = {Review Article},
      keywords     = {Cranial nerves (Other) / Proton therapy (Other) /
                      Radiotherapy (Other) / Salivary gland neoplasms (Other) /
                      Skull base (Other)},
      cin          = {E050},
      ddc          = {610},
      cid          = {I:(DE-He78)E050-20160331},
      pnm          = {315 - Bildgebung und Radioonkologie (POF4-315)},
      pid          = {G:(DE-HGF)POF4-315},
      typ          = {PUB:(DE-HGF)16},
      pubmed       = {pmid:35689095},
      doi          = {10.1007/s00106-022-01188-4},
      url          = {https://inrepo02.dkfz.de/record/180301},
}