000180385 001__ 180385
000180385 005__ 20240229145617.0
000180385 0247_ $$2doi$$a10.1093/jnci/djac117
000180385 0247_ $$2pmid$$apmid:35723569
000180385 0247_ $$2ISSN$$a0027-8874
000180385 0247_ $$2ISSN$$a0198-0157
000180385 0247_ $$2ISSN$$a1460-2105
000180385 0247_ $$2altmetric$$aaltmetric:129978736
000180385 037__ $$aDKFZ-2022-01299
000180385 041__ $$aEnglish
000180385 082__ $$a610
000180385 1001_ $$0P:(DE-He78)bce1fdec5ce564e2666156d96aeabec9$$aJung, Audrey Ying-Chee$$b0$$eFirst author$$udkfz
000180385 245__ $$aDistinct reproductive risk profiles for intrinsic-like breast cancer subtypes: pooled analysis of population-based studies.
000180385 260__ $$aOxford$$bOxford Univ. Press$$c2022
000180385 3367_ $$2DRIVER$$aarticle
000180385 3367_ $$2DataCite$$aOutput Types/Journal article
000180385 3367_ $$0PUB:(DE-HGF)16$$2PUB:(DE-HGF)$$aJournal Article$$bjournal$$mjournal$$s1670934668_19724
000180385 3367_ $$2BibTeX$$aARTICLE
000180385 3367_ $$2ORCID$$aJOURNAL_ARTICLE
000180385 3367_ $$00$$2EndNote$$aJournal Article
000180385 500__ $$a#EA:C020#LA:C020# / 2022 Dec 8;114(12):1706-1719
000180385 520__ $$aReproductive factors have been shown to be differentially associated with risk of estrogen receptor (ER) positive and ER-negative breast cancer. However, their associations with intrinsic-like subtypes are less clear.Analyses included up to 23,353 cases, and 71,072 controls pooled from 31 population-based case-control or cohort studies in the Breast Cancer Association Consortium across 16 countries on 4 continents. Polytomous logistic regression was used to estimate the association between reproductive factors and risk of breast cancer by intrinsic-like subtypes (luminal A-like, luminal B-like, luminal B-HER2-like, HER2-enriched-like, and triple-negative) and by invasiveness. All statistical tests were 2-sided.Compared to nulliparous women, parous women had a lower risk of luminal A-like, luminal B-like, luminal B-HER2-like and HER2-enriched-like disease. This association was apparent only after approximately 10 years since last birth and became stronger with increasing time (odds ratio [OR] = 0.59, 95% confidence interval [CI] = 0.49 to 0.71; and OR = 0.36, 95% CI = 0.28 to 0.46; for multiparous women with luminal A-like tumors 20-<25 years after last birth and 45-<50 years after last birth, respectively). In contrast, parous women had a higher risk of triple-negative breast cancer right after their last birth (for multiparous women: OR = 3.12, 95%CI = 2.02 to 4.83) that was attenuated with time but persisted for decades (OR = 1.03, 95%CI = 0.79 to 1.34, for multiparous women 25 to < 30 years after last birth). Older age at first birth (P-heterogeneity<.001 for triple-negative compared to luminal-A like) and breastfeeding (P-heterogeneity<.001 for triple-negative compared to luminal-A like) were associated with lower risk of triple-negative but not with other disease subtypes. Younger age at menarche was associated with higher risk of all subtypes; older age at menopause was associated with higher risk of luminal A-like but not triple-negative breast cancer. Associations for in situ tumors were similar to luminal A-like.This large and comprehensive study demonstrates a distinct reproductive risk factor profile for triple-negative breast cancer compared to other subtypes, with implications for the understanding of disease etiology and risk prediction.
000180385 536__ $$0G:(DE-HGF)POF4-313$$a313 - Krebsrisikofaktoren und Prävention (POF4-313)$$cPOF4-313$$fPOF IV$$x0
000180385 588__ $$aDataset connected to CrossRef, PubMed, , Journals: inrepo02.dkfz.de
000180385 650_7 $$2Other$$abreast cancer
000180385 650_7 $$2Other$$aintrinsic-like subtypes
000180385 650_7 $$2Other$$areproductive risk factors
000180385 650_7 $$2Other$$atriple-negative
000180385 7001_ $$aAhearn, Thomas U$$b1
000180385 7001_ $$0P:(DE-He78)6b04712f3afe72044d496a25505cb1ea$$aBehrens, Sabine$$b2$$udkfz
000180385 7001_ $$0P:(DE-He78)ab36c38b48e62919a71022ba71822570$$aMiddha, Pooja$$b3
000180385 7001_ $$aBolla, Manjeet K$$b4
000180385 7001_ $$aWang, Qin$$b5
000180385 7001_ $$0P:(DE-He78)d023fdf423d87ee6c710e34dd7581fa0$$aArndt, Volker$$b6$$udkfz
000180385 7001_ $$aAronson, Kristan J$$b7
000180385 7001_ $$aAugustinsson, Annelie$$b8
000180385 7001_ $$aBeane Freeman, Laura E$$b9
000180385 7001_ $$aBecher, Heiko$$b10
000180385 7001_ $$0P:(DE-He78)90d5535ff896e70eed81f4a4f6f22ae2$$aBrenner, Hermann$$b11$$udkfz
000180385 7001_ $$0P:(DE-He78)5323704270b6393dcea70186ffd86bca$$aCanzian, Federico$$b12$$udkfz
000180385 7001_ $$aCarey, Lisa A$$b13
000180385 7001_ $$aConsortium, CTS$$b14$$eCollaboration Author
000180385 7001_ $$aCzene, Kamila$$b15
000180385 7001_ $$aEliassen, A Heather$$b16
000180385 7001_ $$aEriksson, Mikael$$b17
000180385 7001_ $$aEvans, D Gareth$$b18
000180385 7001_ $$aFigueroa, Jonine D$$b19
000180385 7001_ $$aFritschi, Lin$$b20
000180385 7001_ $$aGabrielson, Marike$$b21
000180385 7001_ $$aGiles, Graham G$$b22
000180385 7001_ $$aGuénel, Pascal$$b23
000180385 7001_ $$aHadjisavvas, Andreas$$b24
000180385 7001_ $$aHaiman, Christopher A$$b25
000180385 7001_ $$aHåkansson, Niclas$$b26
000180385 7001_ $$aHall, Per$$b27
000180385 7001_ $$0P:(DE-He78)537e07b3e57b16c7b214fc2242e4326b$$aHamann, Ute$$b28$$udkfz
000180385 7001_ $$aHoppe, Reiner$$b29
000180385 7001_ $$aHopper, John L$$b30
000180385 7001_ $$aHowell, Anthony$$b31
000180385 7001_ $$aHunter, David J$$b32
000180385 7001_ $$0P:(DE-HGF)0$$aHüsing, Anika$$b33
000180385 7001_ $$0P:(DE-He78)4b2dc91c9d1ac33a1c0e0777d0c1697a$$aKaaks, Rudolf$$b34$$udkfz
000180385 7001_ $$aKosma, Veli-Matti$$b35
000180385 7001_ $$aKoutros, Stella$$b36
000180385 7001_ $$aKraft, Peter$$b37
000180385 7001_ $$aLacey, James V$$b38
000180385 7001_ $$aLe Marchand, Loic$$b39
000180385 7001_ $$aLissowska, Jolanta$$b40
000180385 7001_ $$aLoizidou, Maria A$$b41
000180385 7001_ $$aMannermaa, Arto$$b42
000180385 7001_ $$aMaurer, Tabea$$b43
000180385 7001_ $$aMurphy, Rachel A$$b44
000180385 7001_ $$aOlshan, Andrew F$$b45
000180385 7001_ $$aOlsson, Håkan$$b46
000180385 7001_ $$aPatel, Alpa V$$b47
000180385 7001_ $$aPerou, Charles M$$b48
000180385 7001_ $$aRennert, Gad$$b49
000180385 7001_ $$aShibli, Rana$$b50
000180385 7001_ $$aShu, Xiao-Ou$$b51
000180385 7001_ $$aSouthey, Melissa C$$b52
000180385 7001_ $$aStone, Jennifer$$b53
000180385 7001_ $$aTamimi, Rulla M$$b54
000180385 7001_ $$aTeras, Lauren R$$b55
000180385 7001_ $$aTroester, Melissa A$$b56
000180385 7001_ $$aTruong, Thérèse$$b57
000180385 7001_ $$aVachon, Celine M$$b58
000180385 7001_ $$aWang, Sophia S$$b59
000180385 7001_ $$aWolk, Alicja$$b60
000180385 7001_ $$aWu, Anna H$$b61
000180385 7001_ $$aYang, Xiaohong R$$b62
000180385 7001_ $$aZheng, Wei$$b63
000180385 7001_ $$aDunning, Alison M$$b64
000180385 7001_ $$aPharoah, Paul D P$$b65
000180385 7001_ $$aEaston, Douglas F$$b66
000180385 7001_ $$aMilne, Roger L$$b67
000180385 7001_ $$aChatterjee, Nilanjan$$b68
000180385 7001_ $$aSchmidt, Marjanka K$$b69
000180385 7001_ $$aGarcía-Closas, Montserrat$$b70
000180385 7001_ $$0P:(DE-He78)c259d6cc99edf5c7bc7ce22c7f87c253$$aChang-Claude, Jenny$$b71$$eLast author$$udkfz
000180385 773__ $$0PERI:(DE-600)1465951-7$$a10.1093/jnci/djac117$$gp. djac117$$n12$$p1706-1719$$tJournal of the National Cancer Institute$$v114$$x0027-8874$$y2022
000180385 909CO $$ooai:inrepo02.dkfz.de:180385$$pVDB
000180385 9101_ $$0I:(DE-588b)2036810-0$$6P:(DE-He78)bce1fdec5ce564e2666156d96aeabec9$$aDeutsches Krebsforschungszentrum$$b0$$kDKFZ
000180385 9101_ $$0I:(DE-588b)2036810-0$$6P:(DE-He78)6b04712f3afe72044d496a25505cb1ea$$aDeutsches Krebsforschungszentrum$$b2$$kDKFZ
000180385 9101_ $$0I:(DE-588b)2036810-0$$6P:(DE-He78)ab36c38b48e62919a71022ba71822570$$aDeutsches Krebsforschungszentrum$$b3$$kDKFZ
000180385 9101_ $$0I:(DE-588b)2036810-0$$6P:(DE-He78)d023fdf423d87ee6c710e34dd7581fa0$$aDeutsches Krebsforschungszentrum$$b6$$kDKFZ
000180385 9101_ $$0I:(DE-588b)2036810-0$$6P:(DE-He78)90d5535ff896e70eed81f4a4f6f22ae2$$aDeutsches Krebsforschungszentrum$$b11$$kDKFZ
000180385 9101_ $$0I:(DE-588b)2036810-0$$6P:(DE-He78)5323704270b6393dcea70186ffd86bca$$aDeutsches Krebsforschungszentrum$$b12$$kDKFZ
000180385 9101_ $$0I:(DE-588b)2036810-0$$6P:(DE-He78)537e07b3e57b16c7b214fc2242e4326b$$aDeutsches Krebsforschungszentrum$$b28$$kDKFZ
000180385 9101_ $$0I:(DE-588b)2036810-0$$6P:(DE-HGF)0$$aDeutsches Krebsforschungszentrum$$b33$$kDKFZ
000180385 9101_ $$0I:(DE-588b)2036810-0$$6P:(DE-He78)4b2dc91c9d1ac33a1c0e0777d0c1697a$$aDeutsches Krebsforschungszentrum$$b34$$kDKFZ
000180385 9101_ $$0I:(DE-588b)2036810-0$$6P:(DE-He78)c259d6cc99edf5c7bc7ce22c7f87c253$$aDeutsches Krebsforschungszentrum$$b71$$kDKFZ
000180385 9131_ $$0G:(DE-HGF)POF4-313$$1G:(DE-HGF)POF4-310$$2G:(DE-HGF)POF4-300$$3G:(DE-HGF)POF4$$4G:(DE-HGF)POF$$aDE-HGF$$bGesundheit$$lKrebsforschung$$vKrebsrisikofaktoren und Prävention$$x0
000180385 9141_ $$y2022
000180385 915__ $$0StatID:(DE-HGF)0160$$2StatID$$aDBCoverage$$bEssential Science Indicators$$d2021-01-28
000180385 915__ $$0StatID:(DE-HGF)1190$$2StatID$$aDBCoverage$$bBiological Abstracts$$d2021-01-28
000180385 915__ $$0StatID:(DE-HGF)0113$$2StatID$$aWoS$$bScience Citation Index Expanded$$d2021-01-28
000180385 915__ $$0StatID:(DE-HGF)0420$$2StatID$$aNationallizenz$$d2022-11-18$$wger
000180385 915__ $$0StatID:(DE-HGF)0100$$2StatID$$aJCR$$bJNCI-J NATL CANCER I : 2021$$d2022-11-18
000180385 915__ $$0StatID:(DE-HGF)0200$$2StatID$$aDBCoverage$$bSCOPUS$$d2022-11-18
000180385 915__ $$0StatID:(DE-HGF)0300$$2StatID$$aDBCoverage$$bMedline$$d2022-11-18
000180385 915__ $$0StatID:(DE-HGF)0600$$2StatID$$aDBCoverage$$bEbsco Academic Search$$d2022-11-18
000180385 915__ $$0StatID:(DE-HGF)0030$$2StatID$$aPeer Review$$bASC$$d2022-11-18
000180385 915__ $$0StatID:(DE-HGF)0199$$2StatID$$aDBCoverage$$bClarivate Analytics Master Journal List$$d2022-11-18
000180385 915__ $$0StatID:(DE-HGF)0150$$2StatID$$aDBCoverage$$bWeb of Science Core Collection$$d2022-11-18
000180385 915__ $$0StatID:(DE-HGF)1050$$2StatID$$aDBCoverage$$bBIOSIS Previews$$d2022-11-18
000180385 915__ $$0StatID:(DE-HGF)1110$$2StatID$$aDBCoverage$$bCurrent Contents - Clinical Medicine$$d2022-11-18
000180385 915__ $$0StatID:(DE-HGF)1030$$2StatID$$aDBCoverage$$bCurrent Contents - Life Sciences$$d2022-11-18
000180385 915__ $$0StatID:(DE-HGF)9910$$2StatID$$aIF >= 10$$bJNCI-J NATL CANCER I : 2021$$d2022-11-18
000180385 9202_ $$0I:(DE-He78)C020-20160331$$kC020$$lC020 Epidemiologie von Krebs$$x0
000180385 9201_ $$0I:(DE-He78)C020-20160331$$kC020$$lC020 Epidemiologie von Krebs$$x0
000180385 9201_ $$0I:(DE-He78)C070-20160331$$kC070$$lC070 Klinische Epidemiologie und Alternf.$$x1
000180385 9201_ $$0I:(DE-He78)C120-20160331$$kC120$$lPräventive Onkologie$$x2
000180385 9201_ $$0I:(DE-He78)HD01-20160331$$kHD01$$lDKTK HD zentral$$x3
000180385 9201_ $$0I:(DE-He78)C055-20160331$$kC055$$lC055 Genomische Epidemiologie$$x4
000180385 9201_ $$0I:(DE-He78)B072-20160331$$kB072$$lMolekulargenetik des Mammakarzinoms$$x5
000180385 9201_ $$0I:(DE-He78)B070-20160331$$kB070$$lB070 Funktionelle Genomanalyse$$x6
000180385 9200_ $$0I:(DE-He78)C020-20160331$$kC020$$lC020 Epidemiologie von Krebs$$x0
000180385 980__ $$ajournal
000180385 980__ $$aVDB
000180385 980__ $$aI:(DE-He78)C020-20160331
000180385 980__ $$aI:(DE-He78)C070-20160331
000180385 980__ $$aI:(DE-He78)C120-20160331
000180385 980__ $$aI:(DE-He78)HD01-20160331
000180385 980__ $$aI:(DE-He78)C055-20160331
000180385 980__ $$aI:(DE-He78)B072-20160331
000180385 980__ $$aI:(DE-He78)B070-20160331
000180385 980__ $$aUNRESTRICTED