TY  - JOUR
AU  - Jung, Audrey Ying-Chee
AU  - Ahearn, Thomas U
AU  - Behrens, Sabine
AU  - Middha, Pooja
AU  - Bolla, Manjeet K
AU  - Wang, Qin
AU  - Arndt, Volker
AU  - Aronson, Kristan J
AU  - Augustinsson, Annelie
AU  - Beane Freeman, Laura E
AU  - Becher, Heiko
AU  - Brenner, Hermann
AU  - Canzian, Federico
AU  - Carey, Lisa A
AU  - Czene, Kamila
AU  - Eliassen, A Heather
AU  - Eriksson, Mikael
AU  - Evans, D Gareth
AU  - Figueroa, Jonine D
AU  - Fritschi, Lin
AU  - Gabrielson, Marike
AU  - Giles, Graham G
AU  - Guénel, Pascal
AU  - Hadjisavvas, Andreas
AU  - Haiman, Christopher A
AU  - Håkansson, Niclas
AU  - Hall, Per
AU  - Hamann, Ute
AU  - Hoppe, Reiner
AU  - Hopper, John L
AU  - Howell, Anthony
AU  - Hunter, David J
AU  - Hüsing, Anika
AU  - Kaaks, Rudolf
AU  - Kosma, Veli-Matti
AU  - Koutros, Stella
AU  - Kraft, Peter
AU  - Lacey, James V
AU  - Le Marchand, Loic
AU  - Lissowska, Jolanta
AU  - Loizidou, Maria A
AU  - Mannermaa, Arto
AU  - Maurer, Tabea
AU  - Murphy, Rachel A
AU  - Olshan, Andrew F
AU  - Olsson, Håkan
AU  - Patel, Alpa V
AU  - Perou, Charles M
AU  - Rennert, Gad
AU  - Shibli, Rana
AU  - Shu, Xiao-Ou
AU  - Southey, Melissa C
AU  - Stone, Jennifer
AU  - Tamimi, Rulla M
AU  - Teras, Lauren R
AU  - Troester, Melissa A
AU  - Truong, Thérèse
AU  - Vachon, Celine M
AU  - Wang, Sophia S
AU  - Wolk, Alicja
AU  - Wu, Anna H
AU  - Yang, Xiaohong R
AU  - Zheng, Wei
AU  - Dunning, Alison M
AU  - Pharoah, Paul D P
AU  - Easton, Douglas F
AU  - Milne, Roger L
AU  - Chatterjee, Nilanjan
AU  - Schmidt, Marjanka K
AU  - García-Closas, Montserrat
AU  - Chang-Claude, Jenny
TI  - Distinct reproductive risk profiles for intrinsic-like breast cancer subtypes: pooled analysis of population-based studies.
JO  - Journal of the National Cancer Institute
VL  - 114
IS  - 12
SN  - 0027-8874
CY  - Oxford
PB  - Oxford Univ. Press
M1  - DKFZ-2022-01299
SP  - 1706-1719
PY  - 2022
N1  - #EA:C020#LA:C020# / 2022 Dec 8;114(12):1706-1719
AB  - Reproductive factors have been shown to be differentially associated with risk of estrogen receptor (ER) positive and ER-negative breast cancer. However, their associations with intrinsic-like subtypes are less clear.Analyses included up to 23,353 cases, and 71,072 controls pooled from 31 population-based case-control or cohort studies in the Breast Cancer Association Consortium across 16 countries on 4 continents. Polytomous logistic regression was used to estimate the association between reproductive factors and risk of breast cancer by intrinsic-like subtypes (luminal A-like, luminal B-like, luminal B-HER2-like, HER2-enriched-like, and triple-negative) and by invasiveness. All statistical tests were 2-sided.Compared to nulliparous women, parous women had a lower risk of luminal A-like, luminal B-like, luminal B-HER2-like and HER2-enriched-like disease. This association was apparent only after approximately 10 years since last birth and became stronger with increasing time (odds ratio [OR] = 0.59, 95
KW  - breast cancer (Other)
KW  - intrinsic-like subtypes (Other)
KW  - reproductive risk factors (Other)
KW  - triple-negative (Other)
LB  - PUB:(DE-HGF)16
C6  - pmid:35723569
DO  - DOI:10.1093/jnci/djac117
UR  - https://inrepo02.dkfz.de/record/180385
ER  -