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@ARTICLE{Zhu:180681,
      author       = {A. Zhu$^*$ and C. Yuan and J. Pretty and J. S. Ji},
      title        = {{P}lant-based dietary patterns and cognitive function: {A}
                      prospective cohort analysis of elderly individuals in
                      {C}hina (2008-2018).},
      journal      = {Brain and behavior},
      volume       = {12},
      number       = {8},
      issn         = {2162-3279},
      address      = {Malden, Mass.},
      publisher    = {Wiley},
      reportid     = {DKFZ-2022-01481},
      pages        = {e2670},
      year         = {2022},
      note         = {#EA:C070# / 2022 Aug;12(8):e2670},
      abstract     = {Plant-based diets confer health benefits, especially on the
                      prevention of noncommunicable diseases. The relationship
                      between plant-based dietary patterns on cognitive function
                      as a neurological outcome needs more evidence. We aimed to
                      assess the associations between plant-based dietary patterns
                      and cognitive function among Chinese older adults.We used
                      four waves (2008-2018) of the Chinese Longitudinal Healthy
                      Longevity Survey. We included 6136 participants aged 65
                      years and older with normal cognition at baseline. We
                      constructed an overall plant-based diet index (PDI),
                      healthful plant-based diet index (hPDI), and unhealthful
                      plant-based diet index (uPDI) from questionnaires. We used
                      the Mini-Mental State Examination (MMSE) to assess cognitive
                      function. We used the multivariable-adjusted generalized
                      estimating equation to explore the corresponding
                      associations.The multivariable-adjusted models showed
                      inverse associations between plant-based dietary patterns
                      and cognitive function. The highest quartiles of PDI and
                      hPDI were associated with a $55\%$ (odds ratio [OR] = 0.45,
                      $95\%$ CI: 0.39, 0.52) decrease and a $39\%$ (OR = 0.61,
                      $95\%$ CI: 0.54, 0.70) decrease in the odds of cognitive
                      impairment (MMSE < 24), compared with the lowest quartile.
                      In contrast, the highest quartile of uPDI was associated
                      with an increased risk (OR = 2.03, $95\%$ CI: 1.79, 2.31) of
                      cognitive impairment. We did not observe pronounced
                      differences by selected socioeconomic status, physical
                      activity, residential greenness, and APOE ε4 status.Our
                      findings suggested that adherence to healthy plant-based
                      dietary patterns was associated with lower risks of
                      cognitive impairment among older adults, and unhealthy
                      plant-based dietary patterns were related to higher risks of
                      cognitive impairment.},
      keywords     = {cognitive function (Other) / healthy longevity (Other) /
                      plant-based dietary patterns (Other)},
      cin          = {C070},
      ddc          = {610},
      cid          = {I:(DE-He78)C070-20160331},
      pnm          = {313 - Krebsrisikofaktoren und Prävention (POF4-313)},
      pid          = {G:(DE-HGF)POF4-313},
      typ          = {PUB:(DE-HGF)16},
      pubmed       = {pmid:35833240},
      doi          = {10.1002/brb3.2670},
      url          = {https://inrepo02.dkfz.de/record/180681},
}