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100 1 _ |a Zhu, Anna
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245 _ _ |a Plant-based dietary patterns and cognitive function: A prospective cohort analysis of elderly individuals in China (2008-2018).
260 _ _ |a Malden, Mass.
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520 _ _ |a Plant-based diets confer health benefits, especially on the prevention of noncommunicable diseases. The relationship between plant-based dietary patterns on cognitive function as a neurological outcome needs more evidence. We aimed to assess the associations between plant-based dietary patterns and cognitive function among Chinese older adults.We used four waves (2008-2018) of the Chinese Longitudinal Healthy Longevity Survey. We included 6136 participants aged 65 years and older with normal cognition at baseline. We constructed an overall plant-based diet index (PDI), healthful plant-based diet index (hPDI), and unhealthful plant-based diet index (uPDI) from questionnaires. We used the Mini-Mental State Examination (MMSE) to assess cognitive function. We used the multivariable-adjusted generalized estimating equation to explore the corresponding associations.The multivariable-adjusted models showed inverse associations between plant-based dietary patterns and cognitive function. The highest quartiles of PDI and hPDI were associated with a 55% (odds ratio [OR] = 0.45, 95% CI: 0.39, 0.52) decrease and a 39% (OR = 0.61, 95% CI: 0.54, 0.70) decrease in the odds of cognitive impairment (MMSE < 24), compared with the lowest quartile. In contrast, the highest quartile of uPDI was associated with an increased risk (OR = 2.03, 95% CI: 1.79, 2.31) of cognitive impairment. We did not observe pronounced differences by selected socioeconomic status, physical activity, residential greenness, and APOE ε4 status.Our findings suggested that adherence to healthy plant-based dietary patterns was associated with lower risks of cognitive impairment among older adults, and unhealthy plant-based dietary patterns were related to higher risks of cognitive impairment.
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650 _ 7 |a cognitive function
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650 _ 7 |a healthy longevity
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650 _ 7 |a plant-based dietary patterns
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700 1 _ |a Yuan, Changzheng
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700 1 _ |a Pretty, Jules
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700 1 _ |a Ji, John S
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773 _ _ |a 10.1002/brb3.2670
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