TY  - JOUR
AU  - Riemann, Layla Tabea
AU  - Aigner, Christoph Stefan
AU  - Mekle, Ralf
AU  - Speck, Oliver
AU  - Rose, Georg
AU  - Ittermann, Bernd
AU  - Schmitter, Sebastian
AU  - Fillmer, Ariane
TI  - Fourier-based decomposition for simultaneous 2-voxel MRS acquisition with 2SPECIAL.
JO  - Magnetic resonance in medicine
VL  - 88
IS  - 5
SN  - 0740-3194
CY  - New York, NY [u.a.]
PB  - Wiley-Liss
M1  - DKFZ-2022-01647
SP  - 1978-1993
PY  - 2022
N1  - 2022 Nov;88(5):1978-1993
AB  - To simultaneously acquire spectroscopic signals from two MRS voxels using a multi-banded 2 spin-echo, full-intensity acquired localized (2SPECIAL) sequence, and to decompose the signal to their respective regions by a novel voxel-GRAPPA (vGRAPPA) decomposition approach for in vivo brain applications at 7 T.A wideband, uniform rate, smooth truncation (WURST) multi-banded pulse was incorporated into SPECIAL to implement 2SPECIAL for simultaneous multi-voxel spectroscopy (sMVS). To decompose the acquired data, the voxel-GRAPPA decomposition algorithm is introduced, and its performance is compared to the SENSE-based decomposition. Furthermore, the limitations of two-voxel excitation concerning the multi-banded adiabatic inversion pulse, as well as of the combined B0 shim and B1 + adjustments, are evaluated.It was successfully shown that the 2SPECIAL sequence enables sMVS without a significant loss in SNR while reducing the total scan time by 21.6
KW  - 1H brain spectroscopy (Other)
KW  - 2SPECIAL (Other)
KW  - UHF (Other)
KW  - WURST (Other)
KW  - simultaneous multi-voxel spectroscopy (Other)
KW  - voxel-GRAPPA (Other)
LB  - PUB:(DE-HGF)16
C6  - pmid:35906900
DO  - DOI:10.1002/mrm.29369
UR  - https://inrepo02.dkfz.de/record/180922
ER  -