000181428 001__ 181428
000181428 005__ 20240229145647.0
000181428 0247_ $$2doi$$a10.1007/s11307-022-01766-6
000181428 0247_ $$2pmid$$apmid:35999425
000181428 0247_ $$2ISSN$$a1536-1632
000181428 0247_ $$2ISSN$$a1860-2002
000181428 0247_ $$2altmetric$$aaltmetric:134907525
000181428 037__ $$aDKFZ-2022-01996
000181428 041__ $$aEnglish
000181428 082__ $$a570
000181428 1001_ $$0P:(DE-HGF)0$$aKoerber, S. A.$$b0$$eFirst author
000181428 245__ $$aDetecting and Locating the Site of Local Relapse Using 18F-PSMA-1007 Imaging After Primary Treatment of 135 Prostate Cancer Patients-Potential Impact on PSMA-Guided Radiation Therapy.
000181428 260__ $$aCham$$bSpringer Nature Switzerland$$c2023
000181428 3367_ $$2DRIVER$$aarticle
000181428 3367_ $$2DataCite$$aOutput Types/Journal article
000181428 3367_ $$0PUB:(DE-HGF)16$$2PUB:(DE-HGF)$$aJournal Article$$bjournal$$mjournal$$s1678876791_29492
000181428 3367_ $$2BibTeX$$aARTICLE
000181428 3367_ $$2ORCID$$aJOURNAL_ARTICLE
000181428 3367_ $$00$$2EndNote$$aJournal Article
000181428 500__ $$a#EA:E050# / 2023 Apr;25(2):375-383
000181428 520__ $$aDue to limited imaging options, the visualization of a local relapse of prostate cancer used to pose a considerable challenge. However, since the integration of 18F-PSMA-1007-PET/CT into the clinic, a relapsed tumor can now easily be detected by hybrid imaging. The present study aimed to evaluate and map the allocate relapse in a large cohort of prostate cancer patients focusing on individual patient management conclusions for radiation therapy.The current study included 135 men with prostate cancer after primary treatment who underwent 18F-PSMA-1007-PET/CT due to biochemical relapse detecting a local relapse. Imaging data were reassessed and analyzed with regard to relapse locations. For the correlation of tumor foci with clinical data, we used binary logistic regression models as well as the Kruskal-Wallis test and Mann-Whitney test.In total, 69.6% of all patients (mean age: 65 years) underwent prostatectomy while 30.4% underwent radiation therapy. PET imaging detected most frequently a unifocal relapse (72.6%). There was a statistically significantly higher rate of ipsilateral cases among the relapsed tumors. Comparing both treatment approaches, tumors relapsed most commonly within the posterior region after surgery and transition/peripheral zone after radiation therapy, respectively.The present study confirms that 18F-PSMA-1007-PET/CT is highly suitable for the localization and allocation of a local relapse in patients with prostate cancer. The data enable further optimizing dose prescriptions and target volume delineations of radiation therapy in the future.
000181428 536__ $$0G:(DE-HGF)POF4-315$$a315 - Bildgebung und Radioonkologie (POF4-315)$$cPOF4-315$$fPOF IV$$x0
000181428 588__ $$aDataset connected to CrossRef, PubMed, , Journals: inrepo02.dkfz.de
000181428 650_7 $$2Other$$a18F-PSMA-1007
000181428 650_7 $$2Other$$aLocal relapse
000181428 650_7 $$2Other$$aPET/CT
000181428 650_7 $$2Other$$aPSMA
000181428 650_7 $$2Other$$aProstate cancer
000181428 7001_ $$aKroener, R. C.$$b1
000181428 7001_ $$aDendl, K.$$b2
000181428 7001_ $$0P:(DE-HGF)0$$aKratochwil, C.$$b3
000181428 7001_ $$aFink, C. A.$$b4
000181428 7001_ $$aRistau, J.$$b5
000181428 7001_ $$aWinter, E.$$b6
000181428 7001_ $$aHerfarth, K.$$b7
000181428 7001_ $$aHatiboglu, G.$$b8
000181428 7001_ $$aHohenfellner, M.$$b9
000181428 7001_ $$0P:(DE-He78)13a0afba029f5f64dc18b25ef7499558$$aHaberkorn, Uwe$$b10$$udkfz
000181428 7001_ $$0P:(DE-He78)8714da4e45acfa36ce87c291443a9218$$aDebus, Jürgen$$b11$$udkfz
000181428 7001_ $$aGiesel, F. L.$$b12
000181428 773__ $$0PERI:(DE-600)2079211-6$$a10.1007/s11307-022-01766-6$$n2$$p375-383$$tMolecular imaging & biology$$v25$$x1536-1632$$y2023
000181428 909CO $$ooai:inrepo02.dkfz.de:181428$$pVDB
000181428 9101_ $$0I:(DE-588b)2036810-0$$6P:(DE-HGF)0$$aDeutsches Krebsforschungszentrum$$b0$$kDKFZ
000181428 9101_ $$0I:(DE-588b)2036810-0$$6P:(DE-HGF)0$$aDeutsches Krebsforschungszentrum$$b3$$kDKFZ
000181428 9101_ $$0I:(DE-588b)2036810-0$$6P:(DE-He78)13a0afba029f5f64dc18b25ef7499558$$aDeutsches Krebsforschungszentrum$$b10$$kDKFZ
000181428 9101_ $$0I:(DE-588b)2036810-0$$6P:(DE-He78)8714da4e45acfa36ce87c291443a9218$$aDeutsches Krebsforschungszentrum$$b11$$kDKFZ
000181428 9131_ $$0G:(DE-HGF)POF4-315$$1G:(DE-HGF)POF4-310$$2G:(DE-HGF)POF4-300$$3G:(DE-HGF)POF4$$4G:(DE-HGF)POF$$aDE-HGF$$bGesundheit$$lKrebsforschung$$vBildgebung und Radioonkologie$$x0
000181428 9141_ $$y2022
000181428 915__ $$0StatID:(DE-HGF)3002$$2StatID$$aDEAL Springer$$d2021-05-04$$wger
000181428 915__ $$0StatID:(DE-HGF)0160$$2StatID$$aDBCoverage$$bEssential Science Indicators$$d2021-05-04
000181428 915__ $$0StatID:(DE-HGF)0113$$2StatID$$aWoS$$bScience Citation Index Expanded$$d2021-05-04
000181428 915__ $$0StatID:(DE-HGF)0100$$2StatID$$aJCR$$bMOL IMAGING BIOL : 2022$$d2023-08-22
000181428 915__ $$0StatID:(DE-HGF)0200$$2StatID$$aDBCoverage$$bSCOPUS$$d2023-08-22
000181428 915__ $$0StatID:(DE-HGF)0300$$2StatID$$aDBCoverage$$bMedline$$d2023-08-22
000181428 915__ $$0StatID:(DE-HGF)0600$$2StatID$$aDBCoverage$$bEbsco Academic Search$$d2023-08-22
000181428 915__ $$0StatID:(DE-HGF)0030$$2StatID$$aPeer Review$$bASC$$d2023-08-22
000181428 915__ $$0StatID:(DE-HGF)0199$$2StatID$$aDBCoverage$$bClarivate Analytics Master Journal List$$d2023-08-22
000181428 915__ $$0StatID:(DE-HGF)0150$$2StatID$$aDBCoverage$$bWeb of Science Core Collection$$d2023-08-22
000181428 915__ $$0StatID:(DE-HGF)1110$$2StatID$$aDBCoverage$$bCurrent Contents - Clinical Medicine$$d2023-08-22
000181428 915__ $$0StatID:(DE-HGF)9900$$2StatID$$aIF < 5$$d2023-08-22
000181428 9201_ $$0I:(DE-He78)E050-20160331$$kE050$$lE050 KKE Strahlentherapie$$x0
000181428 9201_ $$0I:(DE-He78)E060-20160331$$kE060$$lE060 KKE Nuklearmedizin$$x1
000181428 9201_ $$0I:(DE-He78)HD01-20160331$$kHD01$$lDKTK HD zentral$$x2
000181428 9200_ $$0I:(DE-He78)E050-20160331$$kE050$$lE050 KKE Strahlentherapie$$x0
000181428 980__ $$ajournal
000181428 980__ $$aVDB
000181428 980__ $$aI:(DE-He78)E050-20160331
000181428 980__ $$aI:(DE-He78)E060-20160331
000181428 980__ $$aI:(DE-He78)HD01-20160331
000181428 980__ $$aUNRESTRICTED