TY  - JOUR
AU  - Koerber, S. A.
AU  - Kroener, R. C.
AU  - Dendl, K.
AU  - Kratochwil, C.
AU  - Fink, C. A.
AU  - Ristau, J.
AU  - Winter, E.
AU  - Herfarth, K.
AU  - Hatiboglu, G.
AU  - Hohenfellner, M.
AU  - Haberkorn, Uwe
AU  - Debus, Jürgen
AU  - Giesel, F. L.
TI  - Detecting and Locating the Site of Local Relapse Using 18F-PSMA-1007 Imaging After Primary Treatment of 135 Prostate Cancer Patients-Potential Impact on PSMA-Guided Radiation Therapy.
JO  - Molecular imaging & biology
VL  - 25
IS  - 2
SN  - 1536-1632
CY  - Cham
PB  - Springer Nature Switzerland
M1  - DKFZ-2022-01996
SP  - 375-383
PY  - 2023
N1  - #EA:E050# / 2023 Apr;25(2):375-383
AB  - Due to limited imaging options, the visualization of a local relapse of prostate cancer used to pose a considerable challenge. However, since the integration of 18F-PSMA-1007-PET/CT into the clinic, a relapsed tumor can now easily be detected by hybrid imaging. The present study aimed to evaluate and map the allocate relapse in a large cohort of prostate cancer patients focusing on individual patient management conclusions for radiation therapy.The current study included 135 men with prostate cancer after primary treatment who underwent 18F-PSMA-1007-PET/CT due to biochemical relapse detecting a local relapse. Imaging data were reassessed and analyzed with regard to relapse locations. For the correlation of tumor foci with clinical data, we used binary logistic regression models as well as the Kruskal-Wallis test and Mann-Whitney test.In total, 69.6
KW  - 18F-PSMA-1007 (Other)
KW  - Local relapse (Other)
KW  - PET/CT (Other)
KW  - PSMA (Other)
KW  - Prostate cancer (Other)
LB  - PUB:(DE-HGF)16
C6  - pmid:35999425
DO  - DOI:10.1007/s11307-022-01766-6
UR  - https://inrepo02.dkfz.de/record/181428
ER  -