TY  - JOUR
AU  - Rühle, Alexander
AU  - Nya Yompang, Verlaine Ange
AU  - Spohn, Simon K B
AU  - Stoian, Raluca
AU  - Zamboglou, Constantinos
AU  - Gkika, Eleni
AU  - Grosu, Anca-Ligia
AU  - Nicolay, Nils
AU  - Sprave, Tanja
TI  - Palliative radiotherapy of bone metastases in octogenarians: How do the oldest olds respond? Results from a tertiary cancer center with 288 treated patients.
JO  - Radiation oncology
VL  - 17
IS  - 1
SN  - 1748-717X
CY  - London
PB  - BioMed Central
M1  - DKFZ-2022-02114
SP  - 153
PY  - 2022
N1  - #LA:E055#
AB  - Accompanied by the demographic change, the number of octogenarian cancer patients with bone metastases will increase in the future. Palliative radiotherapy constitutes an effective analgesic treatment; however, as pain perception and bone metabolism change with increasing age, the analgesic efficacy of radiotherapy may be altered in elderly patients. We therefore investigated the treatment outcomes of palliative radiotherapy for bone metastases in octogenarians.Patients between 80 and 89 years undergoing radiotherapy for bone metastases between 2009 and 2019 at a tertiary cancer center were analyzed for patterns-of-care, pain response and overall survival (OS). Logistic regression analyses were carried out to examine parameters associated with pain response, and Cox analyses were conducted to reveal prognostic parameters for OS.A total of 288 patients with 516 irradiated lesions were included in the analysis. The majority (n = 249, 86
KW  - Bone metastases (Other)
KW  - Elderly (Other)
KW  - Geriatric (Other)
KW  - Octogenarians (Other)
KW  - Radiotherapy (Other)
KW  - SINS (Other)
LB  - PUB:(DE-HGF)16
C6  - pmid:36071522
DO  - DOI:10.1186/s13014-022-02122-2
UR  - https://inrepo02.dkfz.de/record/181614
ER  -