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@ARTICLE{Hemminki:181669,
author = {J. Hemminki and A. Försti$^*$ and A. Hemminki and K.
Hemminki$^*$},
title = {{S}urvival trends in solid cancers in the {N}ordic
countries through 50 years.},
journal = {European journal of cancer},
volume = {175},
issn = {0014-2964},
address = {Amsterdam [u.a.]},
publisher = {Elsevier},
reportid = {DKFZ-2022-02153},
pages = {77 - 85},
year = {2022},
note = {#LA:C020#},
abstract = {Global survival studies in cancer have generally shown
favourable development, but studies over extended periods on
populations for which medical care is essentially free of
charge are lacking.We analyse relative 1- and 5-year
survival in all solid cancers in Denmark, Finland, Norway
and Sweden through a 50-year period (1970-2019) using the
NORDCAN database.The most recent survival results showed
three types of patterns. Cancers of very good survival
(5-year survival $∼90\%)$ included common cancers of the
breast and prostate, as well as melanoma. The second
pattern, which included the largest number of cancers,
showed 1-year survival of over $80\%$ and a drop of 10-20
$\%$ units in 5-year survival. The third group consisted of
eight fatal cancers, sharing poor 5-year survival (around
$20\%).$ The 50-year improvement in 1-year survival was
largest (30-50 $\%$ units) in kidney, brain, gallbladder and
liver cancers, and $(∼30\%)$ in colon, small intestinal,
lung, pleural, pancreas and ovarian cancers. Improvements in
5-year survival were highest (40-50 $\%$ units) in prostate
and kidney cancers but remained at 10-20 $\%$ units for the
eight fatal cancers. Survival showed significant sex
preferences for a few cancers.The analysis over a
half-century confirms the progress in 'real-world' cancer
control, and in $84\%$ of patients 5-year survival was
$>60\%.$ Metastases remain a challenge, placing the emphasis
on early detection before metastasis occurs. Novel
therapies, such as immunotherapy which has curative
potential even against metastatic disease, are needed.},
keywords = {Cancer control (Other) / Periodic survival (Other) /
Prognosis (Other) / Treatment (Other)},
cin = {B062 / HD01 / C020},
ddc = {610},
cid = {I:(DE-He78)B062-20160331 / I:(DE-He78)HD01-20160331 /
I:(DE-He78)C020-20160331},
pnm = {313 - Krebsrisikofaktoren und Prävention (POF4-313)},
pid = {G:(DE-HGF)POF4-313},
typ = {PUB:(DE-HGF)16},
pubmed = {pmid:36096040},
doi = {10.1016/j.ejca.2022.08.015},
url = {https://inrepo02.dkfz.de/record/181669},
}